DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31075 and Aldh9a1

DIOPT Version :9

Sequence 1:	NP_001247324.1	Gene:	CG31075 / 43244	FlyBaseID:	FBgn0051075	Length:	508	Species:	Drosophila melanogaster
Sequence 2:	NP_064377.2	Gene:	Aldh9a1 / 56752	MGIID:	1861622	Length:	518	Species:	Mus musculus

Alignment Length:	476	Identity:	181/476 - (38%)
Similarity:	284/476 - (59%)	Gaps:	18/476 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 EFVDSVSGKTFATFNPATSKEIVQVSEGDKADIDLAVKAAKKAFHRDSEWRKLSPLQRTNLMNKL 105
            |.||: || |...|.|||.:.|...:...:.:::|||:.||.||   ..|.|.|.|:|..::.:.
Mouse    45 EPVDA-SG-TEKAFEPATGRVIATFACSGEKEVNLAVENAKAAF---KLWSKKSGLERCQVLLEA 104

  Fly   106 CALMDRDKAFLASLETQDNGKPYAEALFDVTYSILTLQYYAGWTDKFFGDTI--PAGGFVSMTRK 168
            ..::...|..:|::||.:|||...||..||......|:||||......|:.|  |.|.| ..||:
Mouse   105 ARIIKERKDEIATVETINNGKSIFEARLDVDTCWQCLEYYAGLAASMAGEHIQLPGGSF-GYTRR 168

  Fly   169 EPVGVVGQIIPWNYPLLMLAWKWGPALAVGCTIIMKPAEQTPLTALHMAALAKEAGFPAGVINVV 233
            ||:||...|..||||..:..||..||||.|..:|.||:..||::||.:|.:..:||.|.|:.|||
Mouse   169 EPLGVCVGIGAWNYPFQIACWKSAPALACGNAMIFKPSPFTPVSALLLAEIYTKAGAPPGLFNVV 233

  Fly   234 NGFGPTAGAAISAHPDIAKVAFTGSVEIGRIVMQAAATSNLKRVSLELGGKSPVVVFDDADIDFA 298
            .| |...|..:..|.::||::|||||..|..:|:.:| ..:|.::||||||||:::|.|.:::.|
Mouse   234 QG-GAATGQFLCHHREVAKISFTGSVPTGVKIMEMSA-KGVKPITLELGGKSPLIIFSDCNMENA 296

  Fly   299 VETTHEALFSNHGQSCCAGSRTYVHEKIYDEFVAKAAAKAKARKVGNPFEQNVQQGPQIDDDMLT 363
            |:....|.|...||.||.|:|.:|.::|.|:|:.:...:.:..|:|:|..::.:.||.|:...|.
Mouse   297 VKGALMANFLTQGQVCCNGTRVFVQKEIADKFINEVVKQTQKIKLGDPLLEDTRMGPLINAPHLE 361

  Fly   364 KVLGYIESGKKEGAKLQAGGK-------RIGNVGFFVEPTVFSDVKDDMRIAQEEIFGPVQSIFK 421
            :|||:::..|::||.:..||:       ::.: |:::.|.:.::.:|||...:|||||||.||..
Mouse   362 RVLGFVKLAKEQGATVLCGGEVYVPEDPKLKH-GYYMTPCILTNCRDDMTCVKEEIFGPVMSILT 425

  Fly   422 FSSLEEMIDRANNVQYGLAAGVITNDINKALKFANNVDAGSVWINCYDAVLPSTPFGGYKHSGIG 486
            |.:..|:::|||:..:||||||.|.||.:|.:.|..:.||:.:||.|:......||||||.||.|
Mouse   426 FGTEAEVLERANDTTFGLAAGVFTRDIQRAHRVAAELQAGTCYINNYNVSPVELPFGGYKKSGFG 490

  Fly   487 RELGKDGLDNYLETKTITMKL 507
            ||.|:..::.|.:.||:.:::
Mouse   491 RENGRVTIEYYSQLKTVCVEM 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31075	NP_001247324.1	ALDH-SF	33..506	CDD:299846	181/473 (38%)
Aldh9a1	NP_064377.2	ALDH_F9_TMBADH	55..512	CDD:143409	175/464 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000158
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810