DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31075 and aldh9a1b

DIOPT Version :9

Sequence 1:	NP_001247324.1	Gene:	CG31075 / 43244	FlyBaseID:	FBgn0051075	Length:	508	Species:	Drosophila melanogaster
Sequence 2:	XP_009295330.1	Gene:	aldh9a1b / 399481	ZFINID:	ZDB-GENE-040120-5	Length:	539	Species:	Danio rerio

Alignment Length:	503	Identity:	180/503 - (35%)
Similarity:	283/503 - (56%)	Gaps:	28/503 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 HTYAQCEPN-----------YCQLFINNEFVDSVSGKTFATFNPATSKEIVQVSEGDKADIDLAV 77
            |.:.:|..:           :|...::   :..|..|:...|.|||.:.:.::.....|::|.||
Zfish    39 HPWTRCASSGTLQIKDPLNFWCGARVD---LKDVKTKSEPVFEPATGRVLCRLQTCGSAEVDAAV 100

  Fly    78 KAAKKAFHRDSEWRKLSPLQRTNLMNKLCALMDRDKAFLASLETQDNGKPYAEALFDVTYSILTL 142
            :.|..||   ..|||||.::|..:|.:...|:::.:..:|.:|..:|||...||..||..:.|::
Zfish   101 RNASAAF---KVWRKLSGMERARVMLEAARLIEKRREEIAEMEVINNGKSITEARLDVDSARLSI 162

  Fly   143 QYYAGWTDKFFGD--TIPAGGFVSMTRKEPVGVVGQIIPWNYPLLMLAWKWGPALAVGCTIIMKP 205
            :|:||......|.  .:|.|.| :.||:||.||...|..||||..:.|||..||:|.|.:::.||
Zfish   163 EYFAGQATTLSGQHVQLPGGSF-AYTRREPFGVCVGIGAWNYPFQIAAWKSAPAIACGNSMVFKP 226

  Fly   206 AEQTPLTALHMAALAKEAGFPAGVINVVNGFGPTAGAAISAHPDIAKVAFTGSVEIGRIVMQAAA 270
            :..||:||:.:|.:.::||.|.|:.|||.| |...|:.:..||.:.||:|||||..|:.:|: .|
Zfish   227 SPLTPVTAVLLAEIYRQAGAPEGLFNVVQG-GQETGSLLCLHPSVEKVSFTGSVPTGKKIME-MA 289

  Fly   271 TSNLKRVSLELGGKSPVVVFDDADIDFAVETTHEALFSNHGQSCCAGSRTYVHEKIYDEFVAKAA 335
            :..:|.|:||||||||:::|:|.|::.||.....|.|.:.||.|..|:|.:|...|..:|:.:..
Zfish   290 SRGVKAVTLELGGKSPLIIFEDTDLENAVRGALMANFLSQGQVCSNGTRVFVQSSIVPQFLKEVV 354

  Fly   336 AKAKARKVGNPFEQNVQQGPQIDDDMLTKVLGYIESGKKEGAKLQAGGKRIGNV------GFFVE 394
            .:.||..:|:|.....:.|..:....|.|||.|:|..|.|||::..||:.....      |:::.
Zfish   355 RRTKAISIGDPLLDETRMGALVSKAHLDKVLRYVEQAKNEGAQVLCGGEPFSPADPKLKDGYYMT 419

  Fly   395 PTVFSDVKDDMRIAQEEIFGPVQSIFKFSSLEEMIDRANNVQYGLAAGVITNDINKALKFANNVD 459
            |.|.....|||...:|||||||.|:..|.:.:|::.|||:...||||||.|.|:.:|.:...|:.
Zfish   420 PCVLDSCTDDMTCVKEEIFGPVMSVLTFDTEDEVLRRANDSDLGLAAGVFTKDVKRAHRVIENLQ 484

  Fly   460 AGSVWINCYDAVLPSTPFGGYKHSGIGRELGKDGLDNYLETKTITMKL 507
            |||.:||.|:......||||:|.||||||.|:..::.|.:.||:.:::
Zfish   485 AGSCFINNYNITPVEVPFGGFKASGIGRENGQVTIEFYSQLKTVVVEM 532

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31075	NP_001247324.1	ALDH-SF	33..506	CDD:299846	178/480 (37%)
aldh9a1b	XP_009295330.1	ALDH_F9_TMBADH	76..533	CDD:143409	175/463 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584221
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000158
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.740