DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31075 and Aldh3b1

DIOPT Version :9

Sequence 1:	NP_001247324.1	Gene:	CG31075 / 43244	FlyBaseID:	FBgn0051075	Length:	508	Species:	Drosophila melanogaster
Sequence 2:	NP_001006999.1	Gene:	Aldh3b1 / 309147	RGDID:	1359546	Length:	468	Species:	Rattus norvegicus

Alignment Length:	452	Identity:	111/452 - (24%)
Similarity:	181/452 - (40%)	Gaps:	78/452 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 ATSKEIVQVSEGDKADIDLAVKAAKKAFHRDSEWRKLSPLQRTNLMNKLCALMDRDKAFLASLET 121
            |...|:.:::. .:|::|||::..:       .|.|...:.: ||..:|      |.||:
  Rat    56 AFESEVSEIAI-SQAEVDLALRNLR-------SWMKDEKVSK-NLATQL------DSAFI----- 100

  Fly   122 QDNGKPYAEALFDVTYSILTLQYYAGWTDKFFGDTIPAGGFVSMTRKEPVGVVGQIIPWNYPLLM 186
                                                         ||||.|:|..|:||||||.:
  Rat   101 ---------------------------------------------RKEPFGLVLIIVPWNYPLNL 120

  Fly   187 LAWKWGPALAVGCTIIMKPAEQTPLTALHMAALAKEAGFPAGVINVVNGFGPTAGAAISAHPDIA 251
            .......|:|.|..:::||:|.:..|...:|.:.... .......||.| ||.....:..| ...
  Rat   121 TLVPLVGAIAAGNCVVLKPSEISKATEKILAEVLPRY-LDQSCFAVVLG-GPQETGQLLEH-RFD 182

  Fly   252 KVAFTGSVEIGRIVMQAAATSNLKRVSLELGGKSPVVVFDDADIDFAVETTHEALFSNHGQSCCA 316
            .:.|||:..:|:||| |||..:|..::||||||:|..|.|:.|............:.|.||:|.|
  Rat   183 YIFFTGNTYVGKIVM-AAAAKHLTPITLELGGKNPCYVDDNCDPQTVANRVAWFRYFNAGQTCVA 246

  Fly   317 GSRTYVHEKIYDEFVAKAAAKAKARKVGNPFEQNVQQGPQIDDDMLTKVLGYIESGKKEGAKLQA 381
            .......:::.:..| .|...|..|..|:..:.:...|..|:.....::.|.:..|:........
  Rat   247 PDYVLCSQEMQERLV-PALQNAITRFYGDNPQTSPNLGRIINQKHFERLQGLLGCGRVAIGGQSD 310

  Fly   382 GGKRIGNVGFFVEPTVFSDVKDDMRIAQEEIFGPVQSIFKFSSLEEMIDRANNVQYGLAAGVITN 446
            .|:|      ::.|||..||::...:.|||||||:..:...::|:|.|:..|..:..||....:.
  Rat   311 EGER------YIAPTVLVDVQETEPVMQEEIFGPILPLVTVTNLDEAIEFINRREKPLALYAFSK 369

  Fly   447 DINKALKFANNVDAGSVWIN--CYDAVLPSTPFGGYKHSGIGRELGKDGLDNYLETKTITMK 506
            ......:......:|....|  .....|.|.||||...||:||..||...|.:...:...::
  Rat   370 RSQVIKQVLARTSSGGFCGNDGFMHMTLSSLPFGGVGTSGMGRYHGKFSFDTFSNQRACLLR 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31075	NP_001247324.1	ALDH-SF	33..506	CDD:299846	111/450 (25%)
Aldh3b1	NP_001006999.1	ALDH_F3AB	5..447	CDD:143450	111/452 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343945
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.830