DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31075 and Aldh1a7

DIOPT Version :9

Sequence 1:	NP_001247324.1	Gene:	CG31075 / 43244	FlyBaseID:	FBgn0051075	Length:	508	Species:	Drosophila melanogaster
Sequence 2:	XP_017446019.2	Gene:	Aldh1a7 / 29651	RGDID:	620252	Length:	538	Species:	Rattus norvegicus

Alignment Length:	501	Identity:	261/501 - (52%)
Similarity:	336/501 - (67%)	Gaps:	26/501 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 KFDHTYAQCEPNYCQLFINNEFVDSVSGKTFATFNPATSKEIVQVSEGDKADIDLAVKAAKKAFH 85
            |..||         ::|||||:.||||.:.|...||||.:.|..|.||||||:|.|||||::||.
  Rat    45 KIQHT---------KIFINNEWHDSVSHEKFPVINPATEEVICHVEEGDKADVDKAVKAARQAFQ 100

  Fly    86 RDSEWRKLSPLQRTNLMNKLCALMDRDKAFLASLETQDNGKPYAEA-LFDVTYSILTLQYYAGWT 149
            ..|.||.:...:|..|:|||..||:||...||::|:.:.||.:..| :.|...||..|:|:|||.
  Rat   101 IGSPWRTMDASERGRLLNKLADLMERDHLLLATMESMNAGKIFTHAYMLDTEVSIKALKYFAGWA 165

  Fly   150 DKFFGDTIPAGGFV-SMTRKEPVGVVGQIIPWNYPLLMLAWKWGPALAVGCTIIMKPAEQTPLTA 213
            ||..|.|||:.|.| :.||:|.:||.|||||||.||:...||.||||:.|.|:|:||||||||||
  Rat   166 DKIHGQTIPSDGDVFTYTRREHIGVCGQIIPWNGPLVSFIWKIGPALSCGNTVIVKPAEQTPLTA 230

  Fly   214 LHMAALAKEAGFPAGVINVVNGFGPTAGAAISAHPDIAKVAFTGSVEIGRIVMQAAATSNLKRVS 278
            ||||:|.||||||.||:|||.|:|||||||||:|.||.||:||||.|:|.....:...|.|....
  Rat   231 LHMASLIKEAGFPPGVVNVVPGYGPTAGAAISSHMDIDKVSFTGSTEVGPFFGTSNDFSFLFITI 295

  Fly   279 LELGGKSPVVV--------FDDADIDF----AVETTHEALFSNHGQSCCAGSRTYVHEKIYDEFV 331
            |.|..   ::|        |...::.|    |||..|:.:|.:.||.|.|.||.:|.|.||||||
  Rat   296 LHLRN---IIVCVFFRKYFFSHVNVSFAVDSAVEFAHQGVFFHQGQICVAASRLFVEESIYDEFV 357

  Fly   332 AKAAAKAKARKVGNPFEQNVQQGPQIDDDMLTKVLGYIESGKKEGAKLQAGGKRIGNVGFFVEPT 396
            .::..:||...:|||.:..:.||||||.:...|:|..|||||||||||:.||.|.||.||||:||
  Rat   358 RRSVERAKKYVLGNPLDSGMSQGPQIDKEQHVKILDLIESGKKEGAKLECGGGRWGNKGFFVQPT 422

  Fly   397 VFSDVKDDMRIAQEEIFGPVQSIFKFSSLEEMIDRANNVQYGLAAGVITNDINKALKFANNVDAG 461
            |||:|.|:||||:||||||||.|.||.|::|:|.||||..|||||||.|.|:::|:..::.:.||
  Rat   423 VFSNVTDEMRIAKEEIFGPVQQIMKFKSIDEVIKRANNTPYGLAAGVFTKDLDRAITVSSALQAG 487

  Fly   462 SVWINCYDAVLPSTPFGGYKHSGIGRELGKDGLDNYLETKTITMKL 507
            :||:|||.|:....||||:|.||.|||:|:.|:..|.|.||:.||:
  Rat   488 TVWVNCYLALSVQCPFGGFKMSGNGREMGEQGVYEYTELKTVAMKI 533

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31075	NP_001247324.1	ALDH-SF	33..506	CDD:299846	256/486 (53%)
Aldh1a7	XP_017446019.2	ALDH_F1AB_F2_RALDH1	43..532	CDD:143459	259/498 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53964
OrthoDB	1	1.010	-	-		D153834at2759
OrthoFinder	1	1.000	-	-		FOG0000158
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100163
Panther	1	1.100	-	-	O	PTHR11699
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X158
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.930