DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31075 and Aldh3a1

DIOPT Version :9

Sequence 1:	NP_001247324.1	Gene:	CG31075 / 43244	FlyBaseID:	FBgn0051075	Length:	508	Species:	Drosophila melanogaster
Sequence 2:	NP_114178.1	Gene:	Aldh3a1 / 25375	RGDID:	2088	Length:	453	Species:	Rattus norvegicus

Alignment Length:	463	Identity:	133/463 - (28%)
Similarity:	201/463 - (43%)	Gaps:	56/463 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 ADIDLAVKAAKKAFH----RDSEWR--KLSPLQRTNLMNKLCALMDRDKAFLASLETQDNGKPYA 129
            :.|...||.|::||:    |..::|  :|..|||         :::.:...::.....|.||...
  Rat     2 SSISDTVKRAREAFNSGKTRSLQFRIQQLEALQR---------MINENLKSISGALASDLGKNEW 57

  Fly   130 EALFDVTYSIL-----TLQYYAGWTDKFFGDTIPAGGFVSMTRK----------EPVGVVGQIIP 179
            .:.::....:|     |::....|     .:..|    |:.||:          ||:|||..|..
  Rat    58 TSYYEEVAHVLEELDTTIKELPDW-----AEDEP----VAKTRQTQQDDLYIHSEPLGVVLVIGA 113

  Fly   180 WNYPLLMLAWKWGPALAVGCTIIMKPAEQTPLTALHMAALAKEAGFPAGVINVVNGFGPTAGAAI 244
            ||||..:.......|:|.|..:|:||:|.:...|..:|.|..:. ....:..||.|..|.....:
  Rat   114 WNYPFNLTIQPMVGAVAAGNAVILKPSEVSGHMADLLATLIPQY-MDQNLYLVVKGGVPETTELL 177

  Fly   245 SAHPDIAKVAFTGSVEIGRIVMQAAATSNLKRVSLELGGKSPVVVFDDADIDFAVETTHEALFSN 309
            ....|  .:.:|||..:|:||| |||..:|..|:||||||||..|..|.|:|.|........|.|
  Rat   178 KERFD--HIMYTGSTAVGKIVM-AAAAKHLTPVTLELGGKSPCYVDKDCDLDVACRRIAWGKFMN 239

  Fly   310 HGQSCCAGSRTYVHEKIYDEFVAKAAAKAKARKVGNPFEQNVQQGPQIDDDMLTKVLGYIESGKK 374
            .||:|.|.........|.::.|.| ..|:.....|...:|:...|..|:|....:|.|.|::.|
  Rat   240 SGQTCVAPDYILCDPSIQNQIVEK-LKKSLKDFYGEDAKQSRDYGRIINDRHFQRVKGLIDNQK- 302

  Fly   375 EGAKLQAGGKRIGNVGFFVEPTVFSDVKDDMRIAQEEIFGPVQSIFKFSSLEEMIDRANNVQYGL 439
                 .|.|........::.||:..||.....:.||||||||..|....||||.|...|..:..|
  Rat   303 -----VAHGGTWDQSSRYIAPTILVDVDPQSPVMQEEIFGPVMPIVCVRSLEEAIQFINQREKPL 362

  Fly   440 AAGVITNDINKALKFANNVDAGSVWINCYDAV----LPSTPFGGYKHSGIGRELGKDGLDNYLET 500
            |..|.:|:.....|......:|.|..|  |.:    :|:.||||..:||:|...||...:.:...
  Rat   363 ALYVFSNNEKVIKKMIAETSSGGVTAN--DVIVHITVPTLPFGGVGNSGMGAYHGKKSFETFSHR 425

  Fly   501 KTITMKLL 508
            ::..:|.|
  Rat   426 RSCLVKSL 433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31075	NP_001247324.1	ALDH-SF	33..506	CDD:299846	131/459 (29%)
Aldh3a1	NP_114178.1	ALDH_F3AB	5..447	CDD:143450	132/460 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343942
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.830