Protein Alignment CG31075 and ALDH1B1

DIOPT Version :9

• Sequence 1: NP_001247324.1
• Gene: CG31075 / 43244
• FlyBaseID: FBgn0051075
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_000683.3
• Gene: ALDH1B1 / 219
• HGNCID: 407
• Length: 517
• Species: Homo sapiens
• Alignment Length: 511
• Identity: 287/511 - (56%)
• Similarity: 372/511 - (72%)
• Gaps: 8/511 - (1%)

  Fly     5 LQKLLAHQLAVSRKWSKFDHTYAQCEP------NYCQLFINNEFVDSVSGKTFATFNPATSKEIV 63
            |:.|....|::..:.:::....|...|      .|.|||||||:.|:||.|||.|.||.|.:.|.
Human     2 LRFLAPRLLSLQGRTARYSSAAALPSPILNPDIPYNQLFINNEWQDAVSKKTFPTVNPTTGEVIG 66

  Fly    64 QVSEGDKADIDLAVKAAKKAFHRDSEWRKLSPLQRTNLMNKLCALMDRDKAFLASLETQDNGKPY 128
            .|:|||:||:|.|||||::||...|.||::...:|..|:|:|..|::||:.:||||||.|||||:
Human    67 HVAEGDRADVDRAVKAAREAFRLGSPWRRMDASERGRLLNRLADLVERDRVYLASLETLDNGKPF 131

  Fly   129 AEA-LFDVTYSILTLQYYAGWTDKFFGDTIPAGG-FVSMTRKEPVGVVGQIIPWNYPLLMLAWKW 191
            .|: ..|:...|...:|:|||.||:.|.|||..| ....||.|||||.|||||||:||:|..||.
Human   132 QESYALDLDEVIKVYRYFAGWADKWHGKTIPMDGQHFCFTRHEPVGVCGQIIPWNFPLVMQGWKL 196

  Fly   192 GPALAVGCTIIMKPAEQTPLTALHMAALAKEAGFPAGVINVVNGFGPTAGAAISAHPDIAKVAFT 256
            .||||.|.|::||.||||||:||::|:|.||||||.||:|::.|:||||||||:.|.|:.|||||
Human   197 APALATGNTVVMKVAEQTPLSALYLASLIKEAGFPPGVVNIITGYGPTAGAAIAQHVDVDKVAFT 261

  Fly   257 GSVEIGRIVMQAAATSNLKRVSLELGGKSPVVVFDDADIDFAVETTHEALFSNHGQSCCAGSRTY 321
            ||.|:|.::.:||..||||||:||||||||.:|..|||::.|||..|||||.|.||.|||||||:
Human   262 GSTEVGHLIQKAAGDSNLKRVTLELGGKSPSIVLADADMEHAVEQCHEALFFNMGQCCCAGSRTF 326

  Fly   322 VHEKIYDEFVAKAAAKAKARKVGNPFEQNVQQGPQIDDDMLTKVLGYIESGKKEGAKLQAGGKRI 386
            |.|.||:||:.:...|||.||||||||.:.|||||:|.:...:|||||:.|:||||||..||:|.
Human   327 VEESIYNEFLERTVEKAKQRKVGNPFELDTQQGPQVDKEQFERVLGYIQLGQKEGAKLLCGGERF 391

  Fly   387 GNVGFFVEPTVFSDVKDDMRIAQEEIFGPVQSIFKFSSLEEMIDRANNVQYGLAAGVITNDINKA 451
            |..|||::||||..|:||||||:||||||||.:|||..:||:::||||.:|||||.|.|.|::||
Human   392 GERGFFIKPTVFGGVQDDMRIAKEEIFGPVQPLFKFKKIEEVVERANNTRYGLAAAVFTRDLDKA 456

  Fly   452 LKFANNVDAGSVWINCYDAVLPSTPFGGYKHSGIGRELGKDGLDNYLETKTITMKL 507
            :.|...:.||:||:|.|:.|...|||||:|.||.|||||:|||..|.|.||:|:|:
Human   457 MYFTQALQAGTVWVNTYNIVTCHTPFGGFKESGNGRELGEDGLKAYTEVKTVTIKV 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31075	NP_001247324.1	ALDH-SF	33..506	CDD:299846	281/474 (59%)
ALDH1B1	NP_000683.3	ALDH_F1AB_F2_RALDH1	31..511	CDD:143459	281/479 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150013
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53964
OrthoDB	1	1.010	-	-		D153834at2759
OrthoFinder	1	1.000	-	-		FOG0000158
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100163
Panther	1	1.100	-	-	O	PTHR11699
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X158
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	8.760