Protein Alignment CG31075 and Aldh1a2

DIOPT Version :10

• Sequence 1: NP_001247324.1
• Gene: CG31075 / 43244
• FlyBaseID: FBgn0051075
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_033048.2
• Gene: Aldh1a2 / 19378
• MGIID: 107928
• Length: 518
• Species: Mus musculus
• Alignment Length: 480
• Identity: 268/480 - (55%)
• Similarity: 358/480 - (74%)
• Gaps: 2/480 - (0%)

  Fly    30 EPNYCQLFINNEFVDSVSGKTFATFNPATSKEIVQVSEGDKADIDLAVKAAKKAFHRDSEWRKLS 94
            |..|.::|||||:.:|.||:.|...||||.:::.:|.|.||.|||.||:||:.||...|.||::.
Mouse    34 EIKYTKIFINNEWQNSESGRVFPVCNPATGEQVCEVQEADKVDIDKAVQAARLAFSLGSVWRRMD 98

  Fly    95 PLQRTNLMNKLCALMDRDKAFLASLETQDNGKPYAEALF-DVTYSILTLQYYAGWTDKFFGDTIP 158
            ..:|..|::||..|::||:|.||::|:.:.|||:.:|.: |:...|.||:|||||.||..|.|||
Mouse    99 ASERGRLLDKLADLVERDRATLATMESLNGGKPFLQAFYIDLQGVIKTLRYYAGWADKIHGMTIP 163

  Fly   159 A-GGFVSMTRKEPVGVVGQIIPWNYPLLMLAWKWGPALAVGCTIIMKPAEQTPLTALHMAALAKE 222
            . |.:.:.||.||:||.|||||||:||||..||..|||..|.|:::||||||||:||:|.||.||
Mouse   164 VDGDYFTFTRHEPIGVCGQIIPWNFPLLMFTWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKE 228

  Fly   223 AGFPAGVINVVNGFGPTAGAAISAHPDIAKVAFTGSVEIGRIVMQAAATSNLKRVSLELGGKSPV 287
            ||||.||:|::.|:||||||||::|..|.|:|||||.|:|:::.:||..||||||:||||||||.
Mouse   229 AGFPPGVVNILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPN 293

  Fly   288 VVFDDADIDFAVETTHEALFSNHGQSCCAGSRTYVHEKIYDEFVAKAAAKAKARKVGNPFEQNVQ 352
            ::|.|||:|:|||..|:.:|.|.||.|.||||.:|.|.||:|||.::..:||.|.||:||:...:
Mouse   294 IIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVKRSVERAKRRIVGSPFDPTTE 358

  Fly   353 QGPQIDDDMLTKVLGYIESGKKEGAKLQAGGKRIGNVGFFVEPTVFSDVKDDMRIAQEEIFGPVQ 417
            ||||||.....|||..|:||..|||||:.|||.:|..|||:||||||:|.||||||:||||||||
Mouse   359 QGPQIDKKQYNKVLELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQ 423

  Fly   418 SIFKFSSLEEMIDRANNVQYGLAAGVITNDINKALKFANNVDAGSVWINCYDAVLPSTPFGGYKH 482
            .|.:|.:::|:|:||||..:||.|.|.||||||||..::.:.||:||||||:|:...:||||:|.
Mouse   424 EILRFKTMDEVIERANNSDFGLVAAVFTNDINKALMVSSAMQAGTVWINCYNALNAQSPFGGFKM 488

  Fly   483 SGIGRELGKDGLDNYLETKTITMKL 507
            ||.|||:|:.||..|.|.||:|:|:
Mouse   489 SGNGREMGEFGLREYSEVKTVTVKI 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31075	NP_001247324.1	ALDH-SF	33..506	CDD:448367	266/474 (56%)
Aldh1a2	NP_033048.2	ALDH_F1AB_F2_RALDH1	32..512	CDD:143459	267/477 (56%)