Protein Alignment CG31075 and aldh1l2

DIOPT Version :10

• Sequence 1: NP_001247324.1
• Gene: CG31075 / 43244
• FlyBaseID: FBgn0051075
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: XP_002661418.2
• Gene: aldh1l2 / 100333269
• ZFINID: ZDB-GENE-100426-6
• Length: 923
• Species: Danio rerio
• Alignment Length: 495
• Identity: 225/495 - (45%)
• Similarity: 316/495 - (63%)
• Gaps: 15/495 - (3%)

  Fly    26 YAQCEPNYC------QLFINNEFVDSVSGKTFATFNPATSKEIVQVSEGDKADIDLAVKAAKKAF 84
            ||..|.|..      |.|||.:|.|:..|||:.|.||.....|.:||....||:|.||.|||:||
Zfish   429 YATKEVNNMTVKMPYQCFINGKFEDADDGKTYNTVNPTDGSVICKVSYASVADVDKAVSAAKEAF 493

  Fly    85 HRDSEWRKLSPLQRTNLMNKLCALMDRDKAFLASLETQDNGKPYAEAL-FDVTYSILTLQYYAGW 148
            . :..|.|::|..|..|:.:|..||:..:..||::||.|:|..|..|| ..|..||.|.:|:|||
Zfish   494 D-NGPWGKMNPRDRGQLLYRLADLMEEHQEELATIETIDSGAVYTLALKTHVGMSIQTFRYFAGW 557

  Fly   149 TDKFFGDTIPAGGF-----VSMTRKEPVGVVGQIIPWNYPLLMLAWKWGPALAVGCTIIMKPAEQ 208
            .||..|.|||....     ::.|:|||:||...:|||||||:|||||....||.|.|:::|||:.
Zfish   558 CDKIQGSTIPINQARPNRNLTFTKKEPLGVCAIVIPWNYPLMMLAWKSAACLAAGNTLVLKPAQV 622

  Fly   209 TPLTALHMAALAKEAGFPAGVINVVNGFGPTAGAAISAHPDIAKVAFTGSVEIGRIVMQAAATSN 273
            ||||||..|.|..:||.|.||||:|.|.|...|..:|.||||.|:.||||..||:.:|::.|.||
Zfish   623 TPLTALKFAELTIKAGIPKGVINIVPGSGGLVGQRMSEHPDIRKLGFTGSTPIGKQIMKSCAVSN 687

  Fly   274 LKRVSLELGGKSPVVVFDDADIDFAVETTHEALFSNHGQSCCAGSRTYVHEKIYDEFVAKAAAKA 338
            ||:||||||||||:::|.|.|:|.||.....:::.|.|::|.|..|.:|.|.|:||::.:...:.
Zfish   688 LKKVSLELGGKSPLIIFSDCDMDKAVRMGMSSVYFNKGENCIAAGRLFVEESIHDEYIRRVVEEI 752

  Fly   339 KARKVGNPFEQNVQQGPQIDDDMLTKVLGYIESGKKEGAKLQAGGKRIGNVGFFVEPTVFSDVKD 403
            |..|:|:|.:::...|||.....:.|::.|.|.|.||||.|..||:::...|||:|||||:||:|
Zfish   753 KKMKIGDPLDRSTDHGPQNHKAHMDKLVEYCEIGVKEGATLVYGGRQVDRPGFFMEPTVFTDVED 817

  Fly   404 DMRIAQEEIFGPVQSIFKF--SSLEEMIDRANNVQYGLAAGVITNDINKALKFANNVDAGSVWIN 466
            .|.||:||.||||..:.||  ..::.::.|||:.::|||:||.|.|||||:..:..::||:|:||
Zfish   818 HMFIAKEESFGPVMVVSKFKDGDVDGVLSRANDTEFGLASGVFTRDINKAMYVSERLEAGTVFIN 882

  Fly   467 CYDAVLPSTPFGGYKHSGIGRELGKDGLDNYLETKTITMK 506
            .|:....:.||||:|.||.|::||:|.|..||.||.:|::
Zfish   883 TYNKTDVAAPFGGFKQSGFGKDLGEDALHEYLRTKAVTVE 922

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31075	NP_001247324.1	ALDH-SF	33..506	CDD:448367	221/486 (45%)
aldh1l2	XP_002661418.2	FMT_core_FDH_N	23..225	CDD:187716
		FDH_Hydrolase_C	228..327	CDD:187731
		PP-binding	346..407	CDD:425746
		ALDH_F1L_FTFDH	438..923	CDD:143458	221/486 (45%)