DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5521 and zmp:0000001168

DIOPT Version :9

Sequence 1:	NP_001163748.1	Gene:	CG5521 / 43242	FlyBaseID:	FBgn0039466	Length:	1964	Species:	Drosophila melanogaster
Sequence 2:	XP_009301927.1	Gene:	zmp:0000001168 / 555294	ZFINID:	ZDB-GENE-140106-128	Length:	1274	Species:	Danio rerio

Alignment Length:	336	Identity:	79/336 - (23%)
Similarity:	127/336 - (37%)	Gaps:	60/336 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly  1607 LLQRSEKLMRELRNVDLQKCRETHKMAVIYVAAGQEDKGSILRNTSGSSTYEMFVSAL------- 1664
            |...|.|:...|..:|.|......|:.|:|..|||..:..:..|.|....:|.|:..|
Zfish   461 LASTSPKVRDTLLKLDEQGLNFQRKVGVMYCRAGQSTEEDMYNNESAGPVFEEFLDLLGDRVRLK 525

  Fly  1665 GWE-----IDLETHNGFLGGLPRQGCGATAPYYATPFLEVVYHVATRMP-SDSSEAMLLKTRHLG 1723
            |||     :|.:|          ...|..:.|......|:::||:|.:| :.:::..||:.||:|
Zfish   526 GWEKYRAQLDTKT----------DSTGTHSLYTRYQDYEIMFHVSTMLPYTANNKQQLLRKRHIG 580

  Fly  1724 NDEVHIVWSEHNR-DYRRDILPTEFCDVLIVVYP----LRNGLFRVTVNRKPEVPWFGPLANESV 1783
            ||.:.||:.|... .:....:.:.|..|.|:|..    ..|..:||.|.|..::|.||||..:..
Zfish   581 NDIITIVFQEPGALPFTPKAIRSHFQHVFIIVRVHEPCTENTYYRVAVTRSKDIPLFGPLFPKGA 645

  Fly  1784 --VSGACLATLIRATAINASRTKRAALPLYQQFYEERNRSLDSVSSRYKESTTFEDFASRIYNPM 1846
              ...|.....:.|.||||......:..........|...|..::..|..:|..:....     .
Zfish   646 RFPRSAAFRDFLLAKAINAENAAEKSEKFRSMATRTRQEYLKDLAENYVTTTPIDSSTK-----F 705

  Fly  1847 PLSTLGTLRE---SNASSSAAPLASALLDHNRASVKGWVQASIDSGP---------IMGIAPSAS 1899
            ||.:||..|:   ..|..:....|.||:         |....:..|.         ::|:    |
Zfish   706 PLLSLGGKRKDKLKGAKGAELHSAGALV---------WAVTVVQGGENSVSVSLSCLLGV----S 757

  Fly  1900 AGSTAAMEAAT 1910
            |.....:|.:|
Zfish   758 AELVVLIERST 768

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5521	NP_001163748.1	Rap_GAP	1648..1820	CDD:280332	48/191 (25%)
zmp:0000001168	XP_009301927.1	Rap_GAP	502..682	CDD:307998	47/189 (25%)
zmp:0000001168	XP_009301927.1	PDZ_signaling	<841..909	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910