DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5521 and Rap1gap2

DIOPT Version :9

Sequence 1:	NP_001163748.1	Gene:	CG5521 / 43242	FlyBaseID:	FBgn0039466	Length:	1964	Species:	Drosophila melanogaster
Sequence 2:	XP_017452778.1	Gene:	Rap1gap2 / 303298	RGDID:	1304590	Length:	808	Species:	Rattus norvegicus

Alignment Length:	396	Identity:	93/396 - (23%)
Similarity:	153/396 - (38%)	Gaps:	72/396 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly  1613 KLMRELRNVDLQKCRETHKMAVIYVAAGQEDKGSILRNTSGSSTYEMFVSALGWEIDLETHNGFL 1677
            |..:.:.:.|......|.|..|||..|.|..:..:..|...|..::.|:..||..|.|:...||.
  Rat   320 KASQMIVSYDEHDVNNTFKFGVIYQKARQTLEEELFGNNEESPAFKEFLDLLGDTITLQDFKGFR 384

  Fly  1678 GGL--PRQGCGATAPYYATPFLEVVYHVATRMP-SDSSEAMLLKTRHLGNDEVHIVWSEHNRDYR 1739
            |||  .....|..:.|......|:::||:|::| :|.....|.:.||:|||.|.|::.|.|..:.
  Rat   385 GGLDVTHGQTGVESVYTTFRDREIMFHVSTKLPFTDGDTQQLQRKRHIGNDIVAIIFQEENTPFV 449

  Fly  1740 RDILPTEFCDVLIVVYPLRNGL----FRVTVNRKPEVPWFG-PLANESVV-SGACLATLIRATAI 1798
            .|::.:.|....|||.....|.    ::|:|..:.:||.|| ||.:..|. .|......:.....
  Rat   450 PDMIASNFLHAYIVVQAESTGTETPSYKVSVTAREDVPAFGPPLPSPPVFQKGTEFREFLLTKLT 514

  Fly  1799 NA--------------SRTKRAALPLYQQFYEERNRSLDSVSSRYKESTTFED-----------F 1838
            ||              .||:.|   |....::|.:.....:.....|...||:           .
  Rat   515 NAENACCKSDKFAKLEDRTRAA---LLDNLHDELHTHTQVMLGMGPEEDKFENGGHGGFLESFKR 576

  Fly  1839 ASRIYNPMPLSTLGTLRESNASSSAAPLASALLDHN--------------RASVKGWVQASIDSG 1889
            |.|:.:....:.:|:.|:.:..:....|:..:: ||              .|:||...::.|...
  Rat   577 AIRVRSHSMETMVGSQRKLHGGNIPGSLSGGIV-HNSMEVTKTTFSPPVAAATVKNQSRSPIKRR 640

  Fly  1890 PIMGIAPSASAGSTAAMEAATGMSSAS--PRGPRKLGAPFKSVTKKHSLQHIAVGGGAGAGGDTP 1952
              .|:.|...:||....::.|...|||  |:.|          ...||.|.|.      :...:.
  Rat   641 --SGLFPRLHSGSEGQGDSRTRCDSASSTPKTP----------DGGHSSQEIK------SETSSN 687

  Fly  1953 PESPTL 1958
            |.||.:
  Rat   688 PSSPEI 693

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5521	NP_001163748.1	Rap_GAP	1648..1820	CDD:280332	53/194 (27%)
Rap1gap2	XP_017452778.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910