Protein Alignment CG5521 and SIPA1L1

DIOPT Version :10

• Sequence 1: NP_001163748.1
• Gene: CG5521 / 43242
• FlyBaseID: FBgn0039466
• Length: 1964
• Species: Drosophila melanogaster
• Sequence 2: NP_056371.1
• Gene: SIPA1L1 / 26037
• HGNCID: 20284
• Length: 1804
• Species: Homo sapiens
• Alignment Length: 326
• Identity: 79/326 - (24%)
• Similarity: 132/326 - (40%)
• Gaps: 66/326 - (20%)

  Fly  1567 HSTTASFDSLPTR-------TEMPFQYCRLLFSHLGLAGWERRSRTHLLQRSEKLMRELRNVDLQ 1624
            |||..   .||.:       .|:..|..||.|:                  :.|:..:|..:|.|
Human   562 HSTAR---GLPLKEVLEHVVPELNVQCLRLAFN------------------TPKVTEQLMKLDEQ 605

  Fly  1625 KCRETHKMAVIYVAAGQEDKGSILRNTSGSSTYEMFVSALGWEIDLETHNGFLGGLPRQ--GCGA 1687
            ......|:.::|..|||..:..:..|.|....:|.|:..||..:.|:....:...|..:  ..|.
Human   606 GLNYQQKVGIMYCKAGQSTEEEMYNNESAGPAFEEFLQLLGERVRLKGFEKYRAQLDTKTDSTGT 670

  Fly  1688 TAPYYATPFLEVVYHVATRMP-SDSSEAMLLKTRHLGNDEVHIVWSEHN-RDYRRDILPTEFCDV 1750
            .:.|......|:::||:|.:| :.:::..||:.||:|||.|.||:.|.. :.:....:.:.|..|
Human   671 HSLYTTYKDYEIMFHVSTMLPYTPNNKQQLLRKRHIGNDIVTIVFQEPGAQPFSPKNIRSHFQHV 735

  Fly  1751 LIVV---YPLRNGL-FRVTVNRKPEVPWFGP-------LANESVVSGACLATLIRA-TAINASRT 1803
            .::|   .|..:.: :.|.|.|..:||.|||       ....:|.....||.:|.| .|.:.|..
Human   736 FVIVRVHNPCSDSVCYSVAVTRSRDVPSFGPPIPKGVTFPKSNVFRDFLLAKVINAENAAHKSEK 800

  Fly  1804 KRAALPLYQQFY-------EERNRSLD--------SVSSRYKESTTFEDFASRIYNPMPLSTLGT 1853
            .||.....:|.|       ...|..:|        |::|:.||.       |:.|....||::|.
Human   801 FRAMATRTRQEYLKDLAEKNVTNTPIDPSGKFPFISLASKKKEK-------SKPYPGAELSSMGA 858

  Fly  1854 L 1854
            :
Human   859 I 859

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5521	NP_001163748.1	RALGAPB_N	491..619	CDD:466561
		Rap_GAP	1648..1820	CDD:460463	49/194 (25%)
SIPA1L1	NP_056371.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..157
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	277..297
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	380..401
		Rap_GAP	629..809	CDD:460463	47/179 (26%)
		PDZ_SIPA1-like	953..1025	CDD:467227
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1067..1128
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1144..1207
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1268..1306
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1327..1366
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1379..1475
		SPAR_C	1504..1749	CDD:463383
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1505..1536
		ZapB	1737..1792	CDD:428718