DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5521 and Sipa1l1

DIOPT Version :9

Sequence 1:NP_001163748.1 Gene:CG5521 / 43242 FlyBaseID:FBgn0039466 Length:1964 Species:Drosophila melanogaster
Sequence 2:XP_006515747.1 Gene:Sipa1l1 / 217692 MGIID:2443679 Length:1796 Species:Mus musculus


Alignment Length:348 Identity:84/348 - (24%)
Similarity:137/348 - (39%) Gaps:76/348 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly  1567 HSTTASFDSLPTR-------TEMPFQYCRLLFSHLGLAGWERRSRTHLLQRSEKLMRELRNVDLQ 1624
            |||..   .||.:       .|:..|..||.|:                  :.|:..:|..:|.|
Mouse   562 HSTAR---GLPLKEVLEHVIPELNVQCLRLAFN------------------TPKVTEQLMKLDEQ 605

  Fly  1625 KCRETHKMAVIYVAAGQEDKGSILRNTSGSSTYEMFVSALGWEIDLETHNGFLGGLPRQ--GCGA 1687
            ......|:.::|..|||..:..:..|.|....:|.|:..||..:.|:....:...|..:  ..|.
Mouse   606 GLNYQQKVGIMYCKAGQSTEEEMYNNESAGPAFEEFLQLLGERVRLKGFEKYRAQLDTKTDSTGT 670

  Fly  1688 TAPYYATPFLEVVYHVATRMP-SDSSEAMLLKTRHLGNDEVHIVWSEHN-RDYRRDILPTEFCDV 1750
            .:.|......|:::||:|.:| :.:::..||:.||:|||.|.||:.|.. :.:....:.:.|..|
Mouse   671 HSLYTTYKDYEIMFHVSTMLPYTPNNKQQLLRKRHIGNDIVTIVFQEPGAQPFSPKNIRSHFQHV 735

  Fly  1751 LIVV---YPLRNGL-FRVTVNRKPEVPWFGP-------LANESVVSGACLATLIRA-TAINASRT 1803
            .::|   .|....: :.|.|.|..:||.|||       ....:|.....||.:|.| .|.:.|..
Mouse   736 FVIVRAHNPCTESVCYSVAVTRSRDVPSFGPPIPKGVTFPKSNVFRDFLLAKVINAENAAHKSEK 800

  Fly  1804 KRAALPLYQQFY-------EERNRSLD--------SVSSRYKESTTFEDFASRIYNPMPLSTLGT 1853
            .||.....:|.|       ...|..:|        |::|:.||.       |:.|....||::| 
Mouse   801 FRAMATRTRQEYLKDLAEKNVTNTPIDPSGKFPFISLASKKKEK-------SKPYPGAELSSMG- 857

  Fly  1854 LRESNASSSAAPLASALLDHNRA 1876
                     |...|....|:|:|
Mouse   858 ---------AIVWAVRAKDYNKA 871

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5521NP_001163748.1 Rap_GAP 1648..1820 CDD:280332 49/194 (25%)
Sipa1l1XP_006515747.1 Rap_GAP 629..809 CDD:396632 47/179 (26%)
PDZ_signaling 953..1023 CDD:238492
SPAR_C 1496..1741 CDD:403176
ZapB 1729..1784 CDD:399182
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3686
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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