Protein Alignment CG5521 and RapGAP1

DIOPT Version :10

• Sequence 1: NP_001163748.1
• Gene: CG5521 / 43242
• FlyBaseID: FBgn0039466
• Length: 1964
• Species: Drosophila melanogaster
• Sequence 2: XP_061513880.1
• Gene: RapGAP1 / 1271375
• VectorBaseID: AGAMI1_003379
• Length: 1039
• Species: Anopheles gambiae
• Alignment Length: 826
• Identity: 177/826 - (21%)
• Similarity: 253/826 - (30%)
• Gaps: 305/826 - (36%)

  Fly  1392 GGITAGLVTADKQVRVLMRD----------LNGKACWDASILYSEPRNAEEPPKTTPKIQHSQPL 1446
            |..|:|...||.:.|.|.|.          :.|   |..:     ..||:         |:....
Mosquito    61 GSSTSGGAGADDETRSLNRSSRLSPQGRQHMGG---WTTA-----AANAK---------QNGLSA 108

  Fly  1447 DSMATSMVTHTPSPRHTLRHRPAGVLPLAKDMAPDLDQLDDMLAYIGHTSPECVAP-------TV 1504
            .:.|.|..:.|.|| ..||.....:..|.:.:  ...:|||.         .||.|       ||
Mosquito   109 GTTAPSSKSATTSP-DRLRGATHDLFELLERV--QCSRLDDQ---------RCVLPSYFTQVRTV 161

  Fly  1505 SQ--------LNAPT-----ASPLSGNQEAQAISVIL---------NQRLL-----EQEFVTHST 1542
            |.        :|..:     |:|.|.|:....:||.:         |.|.|     ......||.
Mosquito   162 STGTKTRMVCINTRSAEERIANPHSTNESTNNLSVQIPQSMGGGGGNTRSLLRHSNSMSSNPHSN 226

  Fly  1543 QAPSPALRHASSNSS-----------------LQQPDQRSLHSTTASFDSLPTRTEMPFQYCRLL 1590
            ...:||..|..||||                 .||..|....|:.:|..|....|..|.|  |||
Mosquito   227 SNSTPASPHLLSNSSSVHLHHAGAGGGGLHHHQQQHPQYQSQSSVSSQSSSIISTVPPVQ--RLL 289

  Fly  1591 FSHLGLAG-------------------------------WE-------------RR---SRTH-- 1606
            ...|...|                               |.             ||   :|.|
Mosquito   290 EDALSKPGPHPMIIVPNSGGYWVDGTDHDASYEVPSHTTWRVGKIESDDTAKCYRRFFIAREHSN 354

  Fly  1607 ------------LLQRSE--------------------------------------KLMRELRNV 1621
                        |..:||                                      :|:.|..||
Mosquito   355 LVGHDDQLGPVLLSIKSENVANQEHIRILLRLRTGTMHELIPASCLGSSPSPIKMARLLNEQINV 419

  Fly  1622 D------------LQKCRETH------KMAVIYVAAGQEDKGSILRNTSGSSTYEMFVSALGWEI 1668
            |            |....:.|      |..|:|...||..:..:..|:..:..::.|:..||..|
Mosquito   420 DSFMPVLCPKASALIASYDEHVLVTNFKFGVLYQRFGQTAEEELFCNSETTPAFDEFLDVLGQRI 484

  Fly  1669 DLETHNGFLGGLPRQG--CGATAPYYATPFLEVVYHVATRMP-SDSSEAMLLKTRHLGNDEVHIV 1730
            .|..|.|:.|||..|.  .|.||.|......|:::||:|.:| :::....|.:.||:|||.|.||
Mosquito   485 RLRDHKGYRGGLDIQNGHTGDTAVYDVFKEREIMFHVSTLLPYTEADPQQLQRKRHIGNDIVAIV 549

  Fly  1731 WSEHNRDYRRDILPTEFCDVLIVVYPLR----NGLFRVTVNRKPEVPWFGP-LANESVVS-GACL 1789
            :.|.|..:...::.:.|....|||.|:.    |..::::|..:.:||:||| |...||.. |..|
Mosquito   550 FQEENTPFSPAMIASHFLHAFIVVQPIEPNTPNCRYKISVTARDDVPFFGPTLPQPSVFKRGPEL 614

  Fly  1790 ATLIRATAINASRTKRAALPLYQQFYEERNRSLDSVSSRYKESTTFEDF---------------- 1838
            ...:....|||......|....|.....|:..|.::....||.|  .||
Mosquito   615 KEFLLTKLINAENACYKADKFAQLELRTRSSLLQNLVDELKEKT--RDFLGMDVGGGAAGVPTSP 677

  Fly  1839 ------------ASRIYNPMPLSTLGTLRE------SNASSSAAPLASA-----LLDHNRASVKG 1880
                        .||..:.:..:....||.      :|.|..|..:.:|     ...||.
Mosquito   678 TPETPKSEGGFTGSRFIDTVKKALNARLRSQNSDPTNNGSGGAGSVDTATGGGGAKHHNS----- 737

  Fly  1881 WVQASIDSGPIMGIAPSASAGSTAAMEAATGMSSASPRGPRKLGAPFKSVT-------------- 1931
             ::.|.|...::...|....|   |:.....:|.:|..|.||  :|..||.
Mosquito   738 -MKKSKDGTSLVSDMPCGPGG---AVNIGRSLSKSSTTGSRK--SPNDSVASSPDITSRCSLNPT 796

  Fly  1932 ------------------KKH---SLQHIAVGGGAGAGGDTPPESP 1956
                              |.|   |......||.|.|||......|
Mosquito   797 LTNNNNNSNAPNNNNTIGKNHPNGSANGNGAGGNAAAGGANNNNGP 842

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5521	NP_001163748.1	RALGAPB_N	491..619	CDD:466561
		Rap_GAP	1648..1820	CDD:460463	55/180 (31%)
RapGAP1	XP_061513880.1	None