Protein Alignment Tsp97E and CD81

DIOPT Version :10

• Sequence 1: NP_524524.1
• Gene: Tsp97E / 43241
• FlyBaseID: FBgn0039465
• Length: 228
• Species: Drosophila melanogaster
• Sequence 2: XP_054226604.1
• Gene: CD81 / 975
• HGNCID: 1701
• Length: 335
• Species: Homo sapiens
• Alignment Length: 228
• Identity: 53/228 - (23%)
• Similarity: 86/228 - (37%)
• Gaps: 72/228 - (31%)

  Fly    16 NILYVMIG-------FLLIGVGVYARAASIVTNLPIVGGILACGVILICISMLGLAGAVKHHQVM 73
            |:||:.:|       |.   ||:|.              ::|.|.:::.:..||..||::..|.:
Human   142 NLLYLELGDKPAPNTFY---VGIYI--------------LIAVGAVMMFVGFLGCYGAIQESQCL 189

  Fly    74 LFFYMIILFMLFLIQFSIASSCLA-VNSEQ----QQQFAEQGWMTVPTD--------LRKQVQDS 125
            |..:...|.:||..:  :|:.... ||.:|    .:||.:|.......|        :.|...::
Human   190 LGTFFTCLVILFACE--VAAGIWGFVNKDQIAKDVKQFYDQALQQAVVDDDANNAKAVVKTFHET 252

  Fly   126 LKCCGFNATAPSTTSVVPPSNEPSCELINQQCCAHSS------EPDCRCEPCGPLLEDKIDYAFK 184
            |.|||.:.....||||          |.|..|.:.|:      :.||         ..|||..|.
Human   253 LDCCGSSTLTALTTSV----------LKNNLCPSGSNIISNLFKEDC---------HQKIDDLFS 298

  Fly   185 ----LCG----GLGIFFSFTEVLAVFLARRYRN 209
                |.|    .:.:...|..:|::.|....||
Human   299 GKLYLIGIAAIVVAVIMIFEMILSMVLCCGIRN 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp97E	NP_524524.1	Tetraspanin	8..>130	CDD:459767	30/133 (23%)
CD81	XP_054226604.1	Tetraspanin	122..327	CDD:459767	51/222 (23%)