Protein Alignment Tsp97E and CD53

DIOPT Version :10

• Sequence 1: NP_524524.1
• Gene: Tsp97E / 43241
• FlyBaseID: FBgn0039465
• Length: 228
• Species: Drosophila melanogaster
• Sequence 2: NP_000551.1
• Gene: CD53 / 963
• HGNCID: 1686
• Length: 219
• Species: Homo sapiens
• Alignment Length: 237
• Identity: 53/237 - (22%)
• Similarity: 93/237 - (39%)
• Gaps: 68/237 - (28%)

  Fly     9 KNALIALNILYVMIGFLLIGVGVYA----RAASIVTNLP--IVGGI-LACGVILICISMLGLAGA 66
            |..|...|:|:.:.|..::|.|:|.    ....:..|||  .:|.: :..|.|::.::.||..|:
Human    10 KYVLFFFNLLFWICGCCILGFGIYLLIHNNFGVLFHNLPSLTLGNVFVIVGSIIMVVAFLGCMGS 74

  Fly    67 VKHHQVMLFFYMIILFMLFLIQFSIASSCLAVNSEQQQQFAEQG-----------------WMTV 114
            :|.::.:|..:.|:|.::.|.:.::| ..|.|..::..::..:|                 |
Human    75 IKENKCLLMSFFILLLIILLAEVTLA-ILLFVYEQKLNEYVAKGLTDSIHRYHSDNSTKAAW--- 135

  Fly   115 PTDLRKQVQDSLKCCGFNATAPSTTSVVPPSNEPSCELINQQCCAHSSEPDCRCEPCGPLLEDKI 179
                 ..:|..|:|||.|.|:..|:.  ||::.||               |.:.|.|
Human   136 -----DSIQSFLQCCGINGTSDWTSG--PPASCPS---------------DRKVEGC-------- 170

  Fly   180 DYA---------FKLCGGLGIFFSFTEVLAVFLARRYRNQHD 212
             ||         |...|.:.|.....|||.:..|.....|.|
Human   171 -YAKARLWFHSNFLYIGIITICVCVIEVLGMSFALTLNCQID 211

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp97E	NP_524524.1	Tetraspanin	8..>130	CDD:459767	30/144 (21%)
CD53	NP_000551.1	Tetraspanin	9..208	CDD:459767	51/232 (22%)
		CD53_like_LEL	104..186	CDD:239417	21/115 (18%)