Protein Alignment Tsp97E and TSPAN6

DIOPT Version :10

• Sequence 1: NP_524524.1
• Gene: Tsp97E / 43241
• FlyBaseID: FBgn0039465
• Length: 228
• Species: Drosophila melanogaster
• Sequence 2: NP_003261.1
• Gene: TSPAN6 / 7105
• HGNCID: 11858
• Length: 245
• Species: Homo sapiens
• Alignment Length: 261
• Identity: 55/261 - (21%)
• Similarity: 102/261 - (39%)
• Gaps: 73/261 - (27%)

  Fly     6 TCSKNALIALNILYVMIGFLLIGVGVYARAA-----SIV----TNLPIVGGILACGVILICISML 61
            ||.|:.|:....::.:.|.:|:.||::.:.:     |::    ||:|.|  ::|.|.::|.:...
Human    15 TCFKSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNEKATNVPFV--LIATGTVIILLGTF 77

  Fly    62 GLAGAVKHHQVMLFFYMIILFMLFLIQFSIA----------SSCLAVNSEQQ-QQFAEQGWMTVP 115
            |.....:....||..|.:.|.::||::...|          .:....|.|:. :|:...|
Human    78 GCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNYEKALKQYNSTG----- 137

  Fly   116 TDLRK----QVQDSLKCCGFNATAPST-TSVVPPSNEP-SCELINQQCCAHSSEPDCRCEPCGPL 174
             |.|.    ::|::|.|||.......| |:.......| ||               |:.|.|.|.
Human   138 -DYRSHAVDKIQNTLHCCGVTDYRDWTDTNYYSEKGFPKSC---------------CKLEDCTPQ 186

  Fly   175 LE-DK-------------IDYAFKLCGGLGIFFSFTEVLAVFLARRYRNQHDPCYLPARAVFPHD 225
            .: ||             |:....:..|:....:..:::.:|||          |..:||:..:.
Human   187 RDADKVNNEGCFIKVMTIIESEMGVVAGISFGVACFQLIGIFLA----------YCLSRAITNNQ 241

  Fly   226 Y 226
            |
Human   242 Y 242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp97E	NP_524524.1	Tetraspanin	8..>130	CDD:459767	31/145 (21%)
TSPAN6	NP_003261.1	Tetraspanin	17..235	CDD:459767	50/250 (20%)
		TM4SF2_6_like_LEL	112..209	CDD:239414	23/117 (20%)