DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tsp97E and tspan31

DIOPT Version :9

Sequence 1:	NP_001263002.1	Gene:	Tsp97E / 43241	FlyBaseID:	FBgn0039465	Length:	228	Species:	Drosophila melanogaster
Sequence 2:	NP_001017068.1	Gene:	tspan31 / 549822	XenbaseID:	XB-GENE-942512	Length:	215	Species:	Xenopus tropicalis

Alignment Length:	213	Identity:	95/213 - (44%)
Similarity:	140/213 - (65%)	Gaps:	7/213 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MCGGFTCSKNALIALNILYVMIGFLLIGVGVYARAASIVTNLPIVGGILACGVILICISMLGLAG 65
            :|||||||||||.|||::|:::|.|||||..:.:...||:::.|:||::|.||.|:.|:::||.|
Frog     2 VCGGFTCSKNALCALNVVYMLVGLLLIGVAAWGKGFGIVSSIHIIGGVIAIGVFLLLIAIIGLIG 66

  Fly    66 AVKHHQVMLFFYMIILFMLFLIQFSIASSCLAVNSEQQQQFAEQGWMTVPTDLRKQVQDSLKCCG 130
            ||.|||||||.||::|.::|:.||.::.||||:|..||:.|....|..:..|.|..::.:|:|||
Frog    67 AVSHHQVMLFIYMVVLILVFIFQFIVSCSCLAMNRSQQEYFLNTTWTRMSNDTRLNLEKTLECCG 131

  Fly   131 FNATAPSTTSVVPPSNEPSCELINQQCCAHSSEPDCRCEPCGPLLEDKIDYAFKLCGGLGIFFSF 195
            |..|..:....  ..:...|.  ..|.|:.:.:   :|..||..:.:..|.|.|:.||:|:||||
Frog   132 FLNTTDAREEF--KMDVALCS--KAQVCSQNPQ---KCLSCGDKMLNHADEALKILGGVGLFFSF 189

  Fly   196 TEVLAVFLARRYRNQHDP 213
            ||:|.|:||.|||||.||
Frog   190 TEILGVWLAFRYRNQKDP 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tsp97E	NP_001263002.1	Tetraspannin	7..204	CDD:278750	81/196 (41%)
Tsp97E	NP_001263002.1	tetraspanin_LEL	<121..177	CDD:243179	12/55 (22%)
tspan31	NP_001017068.1	Tetraspannin	9..201	CDD:366035	82/198 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	167	1.000	Domainoid score	I3805
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	199	1.000	Inparanoid score	I3674
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1203231at2759
OrthoFinder	1	1.000	-	-		FOG0003591
OrthoInspector	1	1.000	-	-		otm49463
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6361
SonicParanoid	1	1.000	-	-		X2941
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.090