DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tsp97E and tspan13b

DIOPT Version :9

Sequence 1:	NP_001263002.1	Gene:	Tsp97E / 43241	FlyBaseID:	FBgn0039465	Length:	228	Species:	Drosophila melanogaster
Sequence 2:	NP_001005970.1	Gene:	tspan13b / 449797	ZFINID:	ZDB-GENE-041010-45	Length:	203	Species:	Danio rerio

Alignment Length:	212	Identity:	92/212 - (43%)
Similarity:	132/212 - (62%)	Gaps:	19/212 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 CGGFTCSKNALIALNILYVMIGFLLIGVGVYARAASIVTNLPIVGGILACGVILICISMLGLAGA 66
            |.|||||||:|.||||||||:..|:||:..:.:...:|::..:||||:..||.|..:::.||.||
Zfish     3 CAGFTCSKNSLCALNILYVMVSLLMIGIAAWGKCFGLVSSFQVVGGIIGIGVFLFFVALAGLIGA 67

  Fly    67 VKHHQVMLFFYMIILFMLFLIQFSIASSCLAVNSEQQQQFAEQGWMTVPTDLRKQVQDSLKCCGF 131
            :|||||:|||||||||::|::||:::|:|||:|.:||....|.||....| .::.|:.||.||||
Zfish    68 MKHHQVLLFFYMIILFLVFVVQFAVSSACLAINEKQQNHLLEVGWNNSLT-TQRDVEKSLNCCGF 131

  Fly   132 NATAPSTTSVVPPSNEPSCELINQQCCAHSSEPDCRCEPCGPLLEDKIDYAFKLCGGLGIFFSFT 196
            :....:.:...|              |.|.|    .|..|...:::......:..||:|:|||||
Zfish   132 SHMDVNGSCAAP--------------CFHYS----TCTTCAAKIQEHAGEVLRFVGGIGLFFSFT 178

  Fly   197 EVLAVFLARRYRNQHDP 213
            |:|.|:|..|||||.||
Zfish   179 EILGVWLTYRYRNQKDP 195

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tsp97E	NP_001263002.1	Tetraspannin	7..204	CDD:278750	80/196 (41%)
Tsp97E	NP_001263002.1	tetraspanin_LEL	<121..177	CDD:243179	13/55 (24%)
tspan13b	NP_001005970.1	Tetraspannin	8..183	CDD:278750	79/193 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	158	1.000	Domainoid score	I4082
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8671
Inparanoid	1	1.050	191	1.000	Inparanoid score	I3855
OMA	1	1.010	-	-		QHG52462
OrthoDB	1	1.010	-	-		D1203231at2759
OrthoFinder	1	1.000	-	-		FOG0003591
OrthoInspector	1	1.000	-	-		otm25403
orthoMCL	1	0.900	-	-		OOG6_105658
Panther	1	1.100	-	-	O	PTHR19282
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5169
SonicParanoid	1	1.000	-	-		X2941
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	14.010