DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tsp97E and tspan13

DIOPT Version :9

Sequence 1:	NP_001263002.1	Gene:	Tsp97E / 43241	FlyBaseID:	FBgn0039465	Length:	228	Species:	Drosophila melanogaster
Sequence 2:	NP_989184.1	Gene:	tspan13 / 394792	XenbaseID:	XB-GENE-1011146	Length:	201	Species:	Xenopus tropicalis

Alignment Length:	216	Identity:	93/216 - (43%)
Similarity:	134/216 - (62%)	Gaps:	27/216 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MCGGFTCSKNALIALNILYVMIGFLLIGVGVYARAASIVTNLPIVGGILACGVILICISMLGLAG 65
            :|||||||||:|..||:||:|:..|||||..:.....::::|.:||..:|.|::|..|:::||.|
Frog     2 VCGGFTCSKNSLCVLNLLYIMVSLLLIGVAAWGIGFGLISSLRVVGVAVAVGILLFLIALVGLIG 66

  Fly    66 AVKHHQVMLFFYMIILFMLFLIQFSIASSCLAVNSEQQQQFAEQGW---MTVPTDLRKQVQDSLK 127
            |:|||||:|||||||||::|::|||::.:.||:|.:||.|..|.||   ....||:.:    ||.
Frog    67 AIKHHQVLLFFYMIILFLVFVVQFSVSCASLALNKDQQDQLLEVGWNHTNGAHTDIER----SLN 127

  Fly   128 CCGFNATAPSTTSVVPPSNEPSCELINQQCCAHSSEPDCRCEPCGPLLEDKIDYAFKLCGGLGIF 192
            ||||.:.:.:.|                  |..:..||  |..|.|::|.......::.||:|.|
Frog   128 CCGFRSYSKNDT------------------CGATCAPD--CHTCAPIIESHAAEVLRVVGGIGFF 172

  Fly   193 FSFTEVLAVFLARRYRNQHDP 213
            |||||:|.|:|..|||||.||
Frog   173 FSFTEILGVWLTYRYRNQKDP 193

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tsp97E	NP_001263002.1	Tetraspannin	7..204	CDD:278750	80/199 (40%)
Tsp97E	NP_001263002.1	tetraspanin_LEL	<121..177	CDD:243179	13/55 (24%)
tspan13	NP_989184.1	Tetraspannin	9..184	CDD:395265	79/198 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	167	1.000	Domainoid score	I3805
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8671
Inparanoid	1	1.050	199	1.000	Inparanoid score	I3674
OMA	1	1.010	-	-		QHG52462
OrthoDB	1	1.010	-	-		D1203231at2759
OrthoFinder	1	1.000	-	-		FOG0003591
OrthoInspector	1	1.000	-	-		otm49463
Panther	1	1.100	-	-	O	PTHR19282
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5169
SonicParanoid	1	1.000	-	-		X2941
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110