DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tsp97E and tspan31

DIOPT Version :9

Sequence 1:	NP_001263002.1	Gene:	Tsp97E / 43241	FlyBaseID:	FBgn0039465	Length:	228	Species:	Drosophila melanogaster
Sequence 2:	NP_956575.1	Gene:	tspan31 / 393251	ZFINID:	ZDB-GENE-040426-1123	Length:	212	Species:	Danio rerio

Alignment Length:	214	Identity:	96/214 - (44%)
Similarity:	135/214 - (63%)	Gaps:	12/214 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MCGGFTCSKNALIALNILYVMIGFLLIGVGVYARAASIVTNLPIVGGILACGVILICISMLGLAG 65
            :|||||||||||.:||::|:::|.|||.|..:.:...||:::.|:||::|.|..|..|:::||.|
Zfish     2 VCGGFTCSKNALCSLNVVYMLVGLLLIVVAAWGKGFGIVSSIHIIGGVIAVGFFLQLIAIVGLIG 66

  Fly    66 AVKHHQVMLFFYMIILFMLFLIQFSIASSCLAVNSEQQQQFAEQGWMTVPTDLRKQVQDSLKCCG 130
            ||.||||||||||:|||::||.||.::.||||:|..||::..|..|..:..|.|..::..|.|||
Zfish    67 AVHHHQVMLFFYMVILFVVFLFQFGVSCSCLAMNQGQQEKLLESSWKIMSNDTRISLEKKLDCCG 131

  Fly   131 -FNATAPSTTSVVPPSNEPSCELINQQCCAHSSEPDCRCEPCGPLLEDKIDYAFKLCGGLGIFFS 194
             ||:|           |..:..:.:...|.........|..|||.:......|.|:.||:|:|||
Zfish   132 LFNST-----------NLQADIMSDLHLCTSPCTQKKECVTCGPKMLQYSSEALKILGGVGLFFS 185

  Fly   195 FTEVLAVFLARRYRNQHDP 213
            |||:|.|:||.|||||.||
Zfish   186 FTEILGVWLAMRYRNQKDP 204

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tsp97E	NP_001263002.1	Tetraspannin	7..204	CDD:278750	82/197 (42%)
Tsp97E	NP_001263002.1	tetraspanin_LEL	<121..177	CDD:243179	13/56 (23%)
tspan31	NP_956575.1	Tetraspannin	8..201	CDD:278750	87/203 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	158	1.000	Domainoid score	I4082
eggNOG	1	0.900	-	-		E1_KOG3882
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	191	1.000	Inparanoid score	I3855
OMA	1	1.010	-	-		QHG52462
OrthoDB	1	1.010	-	-		D1203231at2759
OrthoFinder	1	1.000	-	-		FOG0003591
OrthoInspector	1	1.000	-	-		otm25403
orthoMCL	1	0.900	-	-		OOG6_105658
Panther	1	1.100	-	-	LDO	PTHR19282
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6361
SonicParanoid	1	1.000	-	-		X2941
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.870