Protein Alignment Tsp97E and CD82

DIOPT Version :10

• Sequence 1: NP_524524.1
• Gene: Tsp97E / 43241
• FlyBaseID: FBgn0039465
• Length: 228
• Species: Drosophila melanogaster
• Sequence 2: XP_047282856.1
• Gene: CD82 / 3732
• HGNCID: 6210
• Length: 308
• Species: Homo sapiens
• Alignment Length: 256
• Identity: 52/256 - (20%)
• Similarity: 98/256 - (38%)
• Gaps: 63/256 - (24%)

  Fly     4 GFTC---SKNALIALNILYVMIGFLLIGVGVY--ARAASIVTNLPIVGG--------ILACGVIL 55
            |..|   :|..|...|:::.::|.:::|.||:  |..:|.::.|.....        .:..|.:.
Human    43 GSACIKVTKYFLFLFNLIFFILGAVILGFGVWILADKSSFISVLQTSSSSLRMGAYVFIGVGAVT 107

  Fly    56 ICISMLGLAGAVKHHQVMLFFYMIILFMLFLIQFSIASSCLAVNSEQQQQFAEQGWMTVPTDLRK 120
            :.:..||..|||...:.:|..|...|.::.:.|.: |.:....|..:.:|  |.|  .:.|:|.:
Human   108 MLMGFLGCIGAVNEVRCLLGLYFAFLLLILIAQVT-AGALFYFNMGKLKQ--EMG--GIVTELIR 167

  Fly   121 Q---------------VQDSLKCCGF--------NATAPSTTSVVPPSNEPSCELINQQ------ 156
            .               ||..:||||:        ||...:...|..|.   |||:..::
Human   168 DYNSSREDSLQDAWDYVQAQVKCCGWVSFYNWTDNAELMNRPEVTYPC---SCEVKGEEDNSLSV 229

  Fly   157 ----CCA---------HSSEPDCRCEPCGPLLEDKIDYAFKLCGGLGIFFSFTEVLAVFLA 204
                |.|         |..:.....|.|...::..:.....:..|:|:..:..|:|.:.|:
Human   230 RKGFCEAPGNRTQSGNHPEDWPVYQEGCMEKVQAWLQENLGIILGVGVGVAIIELLGMVLS 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp97E	NP_524524.1	Tetraspanin	8..>130	CDD:459767	31/146 (21%)
CD82	XP_047282856.1	Tetraspanin	65..295	CDD:459767	47/234 (20%)
		CD37_CD82_like_LEL	147..270	CDD:239413	24/129 (19%)