DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tsp97E and Tspan13

DIOPT Version :9

Sequence 1:	NP_001263002.1	Gene:	Tsp97E / 43241	FlyBaseID:	FBgn0039465	Length:	228	Species:	Drosophila melanogaster
Sequence 2:	NP_001013262.1	Gene:	Tspan13 / 366602	RGDID:	1311788	Length:	204	Species:	Rattus norvegicus

Alignment Length:	213	Identity:	94/213 - (44%)
Similarity:	135/213 - (63%)	Gaps:	18/213 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MCGGFTCSKNALIALNILYVMIGFLLIGVGVYARAASIVTNLPIVGGILACGVILICISMLGLAG 65
            :||||:||||.|.|||:||.::..||||:..:.....::::|.:||.::|.|:.|..|:::||.|
  Rat     2 VCGGFSCSKNCLCALNLLYTLVSLLLIGIAAWGIGFGLISSLRVVGVVIAVGIFLFLIALVGLIG 66

  Fly    66 AVKHHQVMLFFYMIILFMLFLIQFSIASSCLAVNSEQQQQFAEQGWMTVPTDLRKQVQDSLKCCG 130
            |||||||:||||||||.::|::|||::.:|||:|.|||.|..|.||... ...|..:|.:|.|||
  Rat    67 AVKHHQVLLFFYMIILLLVFIVQFSVSCACLALNREQQGQLLEVGWNNT-ASARNDIQRNLNCCG 130

  Fly   131 FNATAPSTTSVVPPSNEPSCELINQQCCAHSSEPDCRCEPCGPLLEDKIDYAFKLCGGLGIFFSF 195
            |....|:.|  .|.|            ||.|::   :|..|.|::.:......:..||:|:||||
  Rat   131 FRNYNPNDT--CPAS------------CAKSNQ---KCSSCAPIIGEYAGEVLRFVGGIGLFFSF 178

  Fly   196 TEVLAVFLARRYRNQHDP 213
            ||:|.|:|..|||||.||
  Rat   179 TEILGVWLTYRYRNQKDP 196

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tsp97E	NP_001263002.1	Tetraspannin	7..204	CDD:278750	82/196 (42%)
Tsp97E	NP_001263002.1	tetraspanin_LEL	<121..177	CDD:243179	16/55 (29%)
Tspan13	NP_001013262.1	Tetraspannin	<55..184	CDD:278750	62/146 (42%)
Tspan13	NP_001013262.1	tetraspanin_LEL	<115..>153	CDD:243179	15/55 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	163	1.000	Domainoid score	I3875
eggNOG	1	0.900	-	-		E1_KOG3882
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8671
Inparanoid	1	1.050	193	1.000	Inparanoid score	I3763
OMA	1	1.010	-	-		QHG52462
OrthoDB	1	1.010	-	-		D1203231at2759
OrthoFinder	1	1.000	-	-		FOG0003591
OrthoInspector	1	1.000	-	-		otm46388
orthoMCL	1	0.900	-	-		OOG6_105658
Panther	1	1.100	-	-	O	PTHR19282
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2941
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840