DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tsp97E and Tsp39D

DIOPT Version :9

Sequence 1:	NP_001263002.1	Gene:	Tsp97E / 43241	FlyBaseID:	FBgn0039465	Length:	228	Species:	Drosophila melanogaster
Sequence 2:	NP_523612.3	Gene:	Tsp39D / 35405	FlyBaseID:	FBgn0032943	Length:	235	Species:	Drosophila melanogaster

Alignment Length:	237	Identity:	60/237 - (25%)
Similarity:	101/237 - (42%)	Gaps:	34/237 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 GGFTCSKNALIALNILYVMIGFLLIGVG-----VYARAASIVTN----LPIVGGILACGVILICI 58
            ||.||.|......|:|:.:.|.|:..||     .||..::.|::    .||:..|:...|.:||
  Fly     4 GGLTCVKYLTFFCNLLFALTGLLIFLVGGMVQLNYAHYSNFVSDHVWTAPIILMIVGAAVAVIC- 67

  Fly    59 SMLGLAGAVKHHQVMLFFYMIILFMLFLIQFSIASSCLAVNSEQQQQFAEQGWMTVP-----TDL 118
             .||..||:|....|:..:.::..::||.:..:..:....::...|....|...|:.     .|.
  Fly    68 -FLGCCGALKESSCMILSFALLAVVIFLFEIGLGLAGYVKHTGLHQIMESQFNSTMQHYKERADY 131

  Fly   119 RKQ---VQDSLKCCGFNATAPSTT----SVVPPSNEPSCELIN----QQCC-AHSSEPDCRCEPC 171
            |..   :|..|.|||.|......|    |.:|.:   .|.:||    ::|. .|:::..| .:..
  Fly   132 RDAWTLLQTELDCCGINGPNDWETVYRNSTLPAA---CCSVINLSEAKECTNTHATQHGC-LQKL 192

  Fly   172 GPLLEDK-IDYAFKLCGGLGIFFSFTEVLAVFLARRYRNQHD 212
            ..:|:.| :..|..:.|..||.. .|.:.|..|.|.:|..:|
  Fly   193 LEILDSKTLILASVVLGVAGIQM-LTILFACCLYRSFRRSYD 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tsp97E	NP_001263002.1	Tetraspannin	7..204	CDD:278750	53/223 (24%)
Tsp97E	NP_001263002.1	tetraspanin_LEL	<121..177	CDD:243179	16/67 (24%)
Tsp39D	NP_523612.3	Tetraspannin	8..227	CDD:278750	54/225 (24%)
Tsp39D	NP_523612.3	tetraspanin_LEL	104..200	CDD:239401	21/99 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3882
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR19282
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910