Protein Alignment Tsp97E and TSPAN3

DIOPT Version :10

• Sequence 1: NP_524524.1
• Gene: Tsp97E / 43241
• FlyBaseID: FBgn0039465
• Length: 228
• Species: Drosophila melanogaster
• Sequence 2: NP_005715.1
• Gene: TSPAN3 / 10099
• HGNCID: 17752
• Length: 253
• Species: Homo sapiens
• Alignment Length: 256
• Identity: 56/256 - (21%)
• Similarity: 92/256 - (35%)
• Gaps: 61/256 - (23%)

  Fly     4 GFTCSKNALIALNILYVMIGFLLIGVGVYARAA---------SIVTNLPIVGGILACGVILICIS 59
            |.|.||..|:.||:::.....:|..||.|....         .:.|.:|.| .|:|.|.:|..|.
Human     5 GITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAV-VIIAVGALLFIIG 68

  Fly    60 MLGLAGAVKHHQVMLFFYMIILFMLFLIQFSIASSCLAVNSEQQQQFAEQGWMTVPTDLRK---- 120
            ::|....::..:..|..::|||.::|:.:..:........::.:.:        |...::|
Human    69 LIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENE--------VDRSIQKVYKT 125

  Fly   121 --------------QVQDSLKCCGF-NATAPSTTSVVPPSNEPSCELINQQCC-----------A 159
                          .||..|.|||. |.:....|.....:...|..|   .||           |
Human   126 YNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPL---SCCRETASNCNGSLA 187

  Fly   160 HSSEPDCRCEPCGPLLEDKIDYAFKLCGGLGIFFSFTEVL-----AVFLARRYRNQHDPCY 215
            |.|  |...|.|..|:..|:...........:.|:..::|     .:.|.||.|   ||.|
Human   188 HPS--DLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSR---DPAY 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp97E	NP_524524.1	Tetraspanin	8..>130	CDD:459767	29/148 (20%)
TSPAN3	NP_005715.1	Tetraspanin	9..235	CDD:459767	47/239 (20%)
		TM4SF8_like_LEL	104..210	CDD:239416	22/118 (19%)