DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6330 and Upp2

DIOPT Version :9

Sequence 1:	NP_733175.1	Gene:	CG6330 / 43240	FlyBaseID:	FBgn0039464	Length:	368	Species:	Drosophila melanogaster
Sequence 2:	XP_011237507.1	Gene:	Upp2 / 76654	MGIID:	1923904	Length:	416	Species:	Mus musculus

Alignment Length:	297	Identity:	136/297 - (45%)
Similarity:	187/297 - (62%)	Gaps:	29/297 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 KAHYDC-----------------AHRSSLQDDETDDAYVKRITRYSDGTVKLRNSNIELMDQDIL 61
            :.|.||                 ::||...|..|.:.  ||       :|.::|..:|.||:|||
Mouse   114 ETHPDCGWPLLAAVQSMASILPASNRSMRPDKNTYER--KR-------SVYVKNPYLEGMDEDIL 169

  Fly    62 YHLALGSESHDLQEMFGDVKFVCMGGTPKRMENFAHFIMNEIGYKLPA-GTQLQDISAYSYRYSM 125
            |||.||:::|:|..|||||||||:||:|.||:.||.|:..|:  :|.. |..::||.|.:.||.|
Mouse   170 YHLDLGTKTHNLPAMFGDVKFVCVGGSPNRMKAFAQFMHKEL--RLEGDGEDIEDICAGTDRYCM 232

  Fly   126 YKVGPVLCVSHGMGTPSVSILMHEMIKLMYHAKCKDPVFIRIGTCGGIGVDGGTVIITEDALDGQ 190
            :|.||||.||||||.||:||::||:|||::||.|.|...|||||.||||:..|:|:||:.|:|..
Mouse   233 FKTGPVLSVSHGMGIPSISIMLHELIKLLHHAHCCDVTIIRIGTSGGIGIAPGSVVITDTAVDSF 297

  Fly   191 LRNSHEFTILGKTIHRPAKLDKKLARELKSLASPDDPYDTIIGKTLCTNDFYEGQGRLDGAFCDF 255
            .:...|..||...:.|..:|||:||.:|.:.:.......|:||.|:||.||||||||||||.|.|
Mouse   298 FKPRFEQVILDNVVTRSTELDKELANDLFNCSREIPNVPTLIGHTMCTYDFYEGQGRLDGALCSF 362

  Fly   256 SENEKMAYLEKLRENGVVNIEMESTIFAALTHHAGIK 292
            |..:|:.||::....||.|||||||:|||:....|::
Mouse   363 SREKKLDYLKRAYRAGVRNIEMESTVFAAMCGLCGLR 399

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6330	NP_733175.1	PNP_UDP_1	50..337	CDD:294213	126/244 (52%)
Upp2	XP_011237507.1	UP_hUPP-like	166..399	CDD:350163	122/234 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	254	1.000	Domainoid score	I2048
eggNOG	1	0.900	-	-		E1_COG2820
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12654
Inparanoid	1	1.050	301	1.000	Inparanoid score	I2663
Isobase	1	0.950	-	0	Normalized mean entropy	S3783
OMA	1	1.010	-	-		QHG59199
OrthoDB	1	1.010	-	-		D1423938at2759
OrthoFinder	1	1.000	-	-		FOG0002165
OrthoInspector	1	1.000	-	-		mtm8805
orthoMCL	1	0.900	-	-		OOG6_101919
Panther	1	1.100	-	-	LDO	PTHR43691
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3955
SonicParanoid	1	1.000	-	-		X2157
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.820