DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6330 and Upp2

DIOPT Version :9

Sequence 1:	NP_733175.1	Gene:	CG6330 / 43240	FlyBaseID:	FBgn0039464	Length:	368	Species:	Drosophila melanogaster
Sequence 2:	NP_001099951.1	Gene:	Upp2 / 295620	RGDID:	1308188	Length:	316	Species:	Rattus norvegicus

Alignment Length:	291	Identity:	144/291 - (49%)
Similarity:	205/291 - (70%)	Gaps:	5/291 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 TVKLRNSNIELMDQDILYHLALGSESHDLQEMFGDVKFVCMGGTPKRMENFAHFIMNEIGYKLPA 109
            :|.:||.:::.||:.|||||.||:::|:|..||||  |||:||:..||:.||.|:..|:|.: ..
  Rat    24 SVYVRNPHLDAMDEGILYHLDLGTKTHNLPAMFGD--FVCVGGSSNRMKAFALFMHKELGLE-GD 85

  Fly   110 GTQLQDISAYSYRYSMYKVGPVLCVSHGMGTPSVSILMHEMIKLMYHAKCKDPVFIRIGTCGGIG 174
            |..::||.|.:.||.|:|.||||.:|||||.||:||::||:|||::||:|.|...|||||.||||
  Rat    86 GDDIEDICAGTDRYCMFKTGPVLSLSHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGIG 150

  Fly   175 VDGGTVIITEDALDGQLRNSHEFTILGKTIHRPAKLDKKLARELKSLASPDDPYDTIIGKTLCTN 239
            :..|:|:||:.|:|...:...|..||...:.|..:|||:||.:|.:.:.....:.|:||.|:||.
  Rat   151 IAPGSVVITDTAVDSFFKPRFEQVILDNVVTRSTELDKELATDLFNCSREIPNFLTLIGHTMCTY 215

  Fly   240 DFYEGQGRLDGAFCDFSENEKMAYLEKLRENGVVNIEMESTIFAALTHHAGIKAAVVCVALLNRL 304
            ||||  ||||||.|.||..:|:.||::..:.||.|||||||:|||:....|::||||||.||:||
  Rat   216 DFYE--GRLDGALCCFSREKKLDYLKRAYKAGVRNIEMESTVFAAMCGLCGLRAAVVCVTLLDRL 278

  Fly   305 NGDQVNAPKEVMNEWQARPQILVSRYIRKVL 335
            ..||:|...:|:.|:|.|||:|:|.:|:|.|
  Rat   279 ESDQINLSHDVLVEYQQRPQLLISNFIKKQL 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6330	NP_733175.1	PNP_UDP_1	50..337	CDD:294213	142/286 (50%)
Upp2	NP_001099951.1	PNP_UDP_1	29..310	CDD:294213	142/286 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	259	1.000	Domainoid score	I1919
eggNOG	1	0.900	-	-		E1_COG2820
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12654
Inparanoid	1	1.050	304	1.000	Inparanoid score	I2570
OMA	1	1.010	-	-		QHG59199
OrthoDB	1	1.010	-	-		D1423938at2759
OrthoFinder	1	1.000	-	-		FOG0002165
OrthoInspector	1	1.000	-	-		mtm9052
orthoMCL	1	0.900	-	-		OOG6_101919
Panther	1	1.100	-	-	LDO	PTHR43691
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2157
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.880