Protein Alignment CG6330 and UPP2

DIOPT Version :10

• Sequence 1: NP_733175.1
• Gene: CG6330 / 43240
• FlyBaseID: FBgn0039464
• Length: 368
• Species: Drosophila melanogaster
• Sequence 2: NP_001128570.1
• Gene: UPP2 / 151531
• HGNCID: 23061
• Length: 374
• Species: Homo sapiens
• Alignment Length: 264
• Identity: 45/264 - (17%)
• Similarity: 86/264 - (32%)
• Gaps: 83/264 - (31%)

  Fly   226 NMFRHMHEIQTGRTSCISHEMLGFDAEGSVINY---KYNEMMTAEEISDRSTKLVTFMDLAGH-- 285
            |:..|:.          |.:.:..|..|:.:||   .:..:.....:|..||.:.:....|.|
Human   354 NVLMHLR----------SFDFIHLDPFGTSVNYLDSAFRNVRNLGIVSVTSTDISSLYAKAQHVA 408

  Fly   286 RRYLKTTVQALSGYCPQHALIVIAA-GNISNMTREHLAIIHALDIS-FSIIVTKIDLAPPDPILF 348
            ||:....:.....|....|.||:|| ...:....:.:.::.|:.:. |.::|.::...|
Human   409 RRHYGCNIVRTEYYKELAARIVVAAVARAAARCNKGIEVLFAVALEHFVLVVVRVLRGP------ 467

  Fly   349 ELKNLLTSIG--YRKVPYLISNQDDVLNANAHQSVEQIVPIFCVSNVTGAGLDLLIQYLYVLSPG 411
                  ||..  .:|:.|||..|                  :|
Human   468 ------TSADETAKKIQYLIHCQ------------------WC---------------------- 486

  Fly   412 ISNAEKERLEQQPIEFQIDEIFRVAEVGTVAGGLLCKGVLTENSQVKVGPLQDGSFFSVTAQVSV 476
                 :||:.|:......:..:|.....       |.|.:...:.:::|||...|.|:......:
Human   487 -----EERIFQKDGNMVEENPYRQLPCN-------CHGSMPGKTAIELGPLWSSSLFNTGFLKRM 539

  Fly   477 LFHA 480
            ||.:
Human   540 LFES 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6330	NP_733175.1	UP_hUPP-like	59..333	CDD:350163	22/113 (19%)
UPP2	NP_001128570.1	UP_hUPP-like	94..368	CDD:350163	3/23 (13%)