Protein Alignment Spag1 and CNS1

DIOPT Version :10

• Sequence 1: NP_651514.1
• Gene: Spag1 / 43239
• FlyBaseID: FBgn0039463
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_009713.1
• Gene: CNS1 / 852452
• SGDID: S000000359
• Length: 385
• Species: Saccharomyces cerevisiae
• Alignment Length: 267
• Identity: 69/267 - (25%)
• Similarity: 115/267 - (43%)
• Gaps: 37/267 - (13%)

  Fly   160 YRKWDKYDP---DEEILRMDLNEERDQEQREKIISNHSKSVTTDKLQSERDSLYERLQAQ-LKNL 220
            |.|..||.|   |.| |...|:|.:|:...|.:...:.......||.....:..|.::.: ||.|
Yeast    10 YTKPQKYVPGPGDPE-LPPQLSEFKDKTSDEILKEMNRMPFFMTKLDETDGAGGENVELEALKAL 73

  Fly   221 S-QLEKEQFAERHRLRGNESFKAKEYENAIEEYNCSIIYDPENA---VHAYNNRAVAHLKLKKYF 281
            : :.|..:.||..:.:|||.:|||.:::|.|.|:..:..:.|:.   ...|.|||...|:||.|.
Yeast    74 AYEGEPHEIAENFKKQGNELYKAKRFKDARELYSKGLAVECEDKSINESLYANRAACELELKNYR 138

  Fly   282 SAISDCQACLQIDPMNIKAHLRMAEAHNAEGKHLESLNVYKKLLDF-----EPDNAIAKKAVEKL 341
            ..|.||...|.|:|.|:|.:.|.::|.    ..|..|...|....|     :|:|    |::..:
Yeast   139 RCIEDCSKALTINPKNVKCYYRTSKAF----FQLNKLEEAKSAATFANQRIDPEN----KSILNM 195

  Fly   342 TSMLGEVAPSSATRLIIEEIDPPQLKTSEPKKEAEKSEPTVVK-KPEPVVSAKKPPPIKDYDLAE 405
            .|::              :....:||..|.|::.|..|....| ..|..::.:....||.:...|
Yeast   196 LSVI--------------DRKEQELKAKEEKQQREAQERENKKIMLESAMTLRNITNIKTHSPVE 246

  Fly   406 LVKPNRM 412
            |:...::
Yeast   247 LLNEGKI 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spag1	NP_651514.1	NlpI	<229..373	CDD:443815	41/151 (27%)
		TPR repeat	229..257	CDD:276809	11/27 (41%)
		TPR repeat	262..293	CDD:276809	12/33 (36%)
		TPR repeat	298..326	CDD:276809	6/27 (22%)
CNS1	NP_009713.1	3a0801s09	68..>218	CDD:273380	47/171 (27%)
		TPR repeat	83..111	CDD:276809	11/27 (41%)
		TPR repeat	120..150	CDD:276809	12/29 (41%)
		CTWD_TTC4	221..374	CDD:439175	6/33 (18%)