DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spag1 and ODAD4

DIOPT Version :9

Sequence 1:NP_651514.1 Gene:Spag1 / 43239 FlyBaseID:FBgn0039463 Length:469 Species:Drosophila melanogaster
Sequence 2:NP_113609.1 Gene:ODAD4 / 83538 HGNCID:25280 Length:672 Species:Homo sapiens


Alignment Length:189 Identity:45/189 - (23%)
Similarity:72/189 - (38%) Gaps:44/189 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   230 ERHRLRGNESFKAKEYENAI----EEYNCSIIYDPENAVHAYNNRAVAHLKLKKYFSAISDCQAC 290
            ||..|.|..|..|:.:.||:    .:.||.:.            |:...||:.....::.|.:|.
Human    21 ERLYLCGEFSKAAQSFSNALYLQDGDKNCLVA------------RSKCFLKMGDLERSLKDAEAS 73

  Fly   291 LQIDPMNIKAHLRMAEAHNAEGKHLESLNVYKKLLDFEPDNAI---AKKAVEKLTSMLGEVAPSS 352
            ||.||...|..|:.||.....|....:|..|.:.....||...   .:||.|.:.:.:|  :|||
Human    74 LQSDPAFCKGILQKAETLYTMGDFEFALVFYHRGYKLRPDREFRVGIQKAQEAINNSVG--SPSS 136

  Fly   353 ATRLIIEEIDPPQLKTSEPKKEAEKSEPTVVKKPEPVVSAKKPPPIKDYDLAELVKPNR 411
            .                  |.|.:.....:.|:.|.:.:.:||.|:|     .|:.|.:
Human   137 I------------------KLENKGDLSFLSKQAENIKAQQKPQPMK-----HLLHPTK 172

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spag1NP_651514.1 TPR_11 229..295 CDD:290150 17/68 (25%)
TPR repeat 229..257 CDD:276809 10/30 (33%)
TPR repeat 262..293 CDD:276809 6/30 (20%)
TPR_11 266..329 CDD:290150 16/62 (26%)
TPR 266..297 CDD:197478 9/30 (30%)
TPR repeat 298..326 CDD:276809 7/27 (26%)
ODAD4NP_113609.1 TPR 1. /evidence=ECO:0000255 13..46 8/24 (33%)
TPR_11 16..78 CDD:290150 17/68 (25%)
TPR repeat 16..41 CDD:276809 8/19 (42%)
TPR repeat 46..76 CDD:276809 8/41 (20%)
TPR 2. /evidence=ECO:0000255 48..80 11/43 (26%)
TPR_11 49..112 CDD:290150 17/74 (23%)
TPR 3. /evidence=ECO:0000255 81..114 8/32 (25%)
TPR repeat 81..109 CDD:276809 7/27 (26%)
TPR 4. /evidence=ECO:0000255 275..311
TPR repeat 311..349 CDD:276809
TPR_12 316..385 CDD:290160
TPR 5. /evidence=ECO:0000255 320..353
TPR 6. /evidence=ECO:0000255 360..393
TPR repeat 360..385 CDD:276809
TPR_12 361..429 CDD:290160
TPR 7. /evidence=ECO:0000255 397..430
TPR_12 398..468 CDD:290160
TPR repeat 431..465 CDD:276809
TPR 8. /evidence=ECO:0000255 437..470
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 527..672
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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