Protein Alignment Spag1 and TSK

DIOPT Version :10

• Sequence 1: NP_651514.1
• Gene: Spag1 / 43239
• FlyBaseID: FBgn0039463
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_188503.2
• Gene: TSK / 821404
• AraportID: AT3G18730
• Length: 1311
• Species: Arabidopsis thaliana
• Alignment Length: 524
• Identity: 100/524 - (19%)
• Similarity: 194/524 - (37%)
• Gaps: 134/524 - (25%)

  Fly    24 HVEKCTNARE-MEKIVQILRSGEEGHYPDLQRCAEEKLKALKPDSKLFRYEEQIKQSTDLDKTEL 87
            |::....|.: :||.....:.|...|...|:  :|:..:|::...|.|:...::.|..    .|.
plant    92 HLQLAEEANDTVEKQRACTQLGRTYHEMFLK--SEDDCEAIQSAKKYFKKAMELAQIL----KEK 150

  Fly    88 KPILDWTDAIKTKDNALNELKKVKQNLNLP-SVRKLSKIDLEKESKTE-KPKPAPKATSPSNTKN 150
            .|..:.:..::...||.|.:..:..:|:.| :.|.:.|..|:...:.| :...|.::....|..|
plant   151 PPPGESSGFLEEYINAHNNIGMLDLDLDNPEAARTILKKGLQICDEEEVREYDAARSRLHHNLGN 215

  Fly   151 KEARIKSTDYRKWDKYDPDEEILRMDLN---------------------EERDQEQREKIISNHS 194
            ....::|     ||:   .::.:.||:|                     ..:.|:..:.::. :.
plant   216 VFMALRS-----WDE---AKKHIEMDINICHKINHVQGEAKGYINLAELHNKTQKYIDALLC-YG 271

  Fly   195 KSVTTDKLQSERDSLYERLQ-------AQLKNLSQLEKEQF------AERHRLRGNESFKAKEYE 246
            |:.:..|...:..:|.|:::       ..:|.:.:|.:|:.      ||....:|.    ::|.:
plant   272 KASSLAKSMQDESALVEQIEHNTKIVKKSMKVMEELREEELMLKKLSAEMTDAKGT----SEERK 332

  Fly   247 NAIEEYNC--SIIYDPENAVHAYNNRAVAHLKLKKYFSAISDCQAC------------------L 291
            :.::...|  |:| |..:.|.|:    :.||:..|....||| :.|                  |
plant   333 SMLQVNACLGSLI-DKSSMVFAW----LKHLQYSKRKKKISD-ELCDKEKLSDAFMIVGESYQNL 391

  Fly   292 QIDPMNIKAHLRMAEAH----NAEGKHLESLNVYK----------KLLDFEPDNAIAKKAVEKLT 342
            :....::|..:|..|.|    |.||:.|..:|:..          .|..:|....||.||  .|.
plant   392 RNFRKSLKWFIRSYEGHEAIGNLEGQALAKINIGNGLDCIGEWTGALQAYEEGYRIALKA--NLP 454

  Fly   343 SM---------------LGEVAPSSATRLIIEEIDPPQLKTSEPKKEAEKSEPTVVK-------- 384
            |:               .|....:|..:..|:     .||.||..::||.|......
plant   455 SIQLSALEDIHYIHMMRFGNAQKASELKETIQ-----NLKESEHAEKAECSTQDECSETDSEGHA 514

  Fly   385 -----KPEPVVSAKKPPPIKDYDLAELVKPNRMVKSNLVSAAEALGNKMQASKGGAPKKPQSPPM 444
                 :|....|.:.|..::...||:|.:.|..|.  |:|..:. |.::...|..:.|:......
plant   515 NVSNDRPNACSSPQTPNSLRSERLADLDEANDDVP--LISFLQP-GKRLFKRKQVSGKQDADTDQ 576

  Fly   445 TPKE 448
            |.|:
plant   577 TKKD 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spag1	NP_651514.1	NlpI	<229..373	CDD:443815	42/192 (22%)
		TPR repeat	229..257	CDD:276809	6/29 (21%)
		TPR repeat	262..293	CDD:276809	10/48 (21%)
		TPR repeat	298..326	CDD:276809	10/41 (24%)
TSK	NP_188503.2	TPR_12	24..98	CDD:315987	1/5 (20%)
		TPR repeat	26..58	CDD:276809
		TPR repeat	68..94	CDD:276809	1/1 (100%)
		TPR	72..>293	CDD:440225	37/215 (17%)
		TPR repeat	105..143	CDD:276809	8/39 (21%)
		TPR repeat	164..192	CDD:276809	7/27 (26%)
		TPR repeat	206..236	CDD:276809	7/37 (19%)
		TPR repeat	247..273	CDD:276809	1/26 (4%)
		leucine-rich repeat	811..830	CDD:275380
		leucine-rich repeat	831..861	CDD:275380
		RNA1	<843..1076	CDD:444072
		leucine-rich repeat	867..887	CDD:275380
		leucine-rich repeat	900..925	CDD:275380
		leucine-rich repeat	926..953	CDD:275380
		leucine-rich repeat	954..984	CDD:275380
		leucine-rich repeat	985..1007	CDD:275380
		leucine-rich repeat	1008..1037	CDD:275380
		RNA1	<1031..>1166	CDD:444072
		leucine-rich repeat	1038..1059	CDD:275380
		leucine-rich repeat	1060..1094	CDD:275380
		leucine-rich repeat	1095..1123	CDD:275380
		leucine-rich repeat	1124..1151	CDD:275380