DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Spag1 and Ttc32

DIOPT Version :9

Sequence 1:	NP_651514.1	Gene:	Spag1 / 43239	FlyBaseID:	FBgn0039463	Length:	469	Species:	Drosophila melanogaster
Sequence 2:	NP_083597.1	Gene:	Ttc32 / 75516	MGIID:	1922766	Length:	148	Species:	Mus musculus

Alignment Length:	172	Identity:	41/172 - (23%)
Similarity:	59/172 - (34%)	Gaps:	62/172 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   236 GNES----------FKAKEYENAIEEYN------------CSIIYDPENAVHAYNNRAVAHLKLK 278
            |.||          |...|:..|.|.|:            ||    ||:...|||||...
Mouse     9 GGESSAALATAQARFSRGEFAEARELYSAFIGQCARHGSKCS----PEDLATAYNNRGQT----- 64

  Fly   279 KYFS-----AISDCQACLQIDPMNIKAHLRMAEAHNAEGKHLESLNVYKKLLDFEP--DNAIAKK 336
            ||||     |:.|..:.::|.|.....:..........|...|:|..:||.||..|  .:|:.
Mouse    65 KYFSVDFYEAMDDYTSAIEILPSFEVPYYNRGLIRYRLGYFDEALEDFKKALDLNPGFQDAVL-- 127

  Fly   337 AVEKLTSMLGEVAPSSATRLIIEEIDPPQLKTSEPKKEAEKS 378
                           |..:.|::       |..:.::.||||
Mouse   128 ---------------SLKQTILD-------KEEKQRRNAEKS 147

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spag1	NP_651514.1	TPR_11	229..295	CDD:290150	24/85 (28%)
		TPR repeat	229..257	CDD:276809	10/42 (24%)
		TPR repeat	262..293	CDD:276809	11/35 (31%)
		TPR_11	266..329	CDD:290150	20/67 (30%)
		TPR	266..297	CDD:197478	13/35 (37%)
		TPR repeat	298..326	CDD:276809	5/27 (19%)
Ttc32	NP_083597.1	TPR_11	11..86	CDD:290150	23/83 (28%)
		TPR 1	12..45		6/32 (19%)
		TPR_11	55..120	CDD:290150	20/69 (29%)
		TPR 2	55..88		13/37 (35%)
		TPR repeat	55..83	CDD:276809	11/32 (34%)
		TPR repeat	88..118	CDD:276809	6/29 (21%)
		TPR 3	89..122		8/32 (25%)
		TPR_1	92..122	CDD:278916	8/29 (28%)
		TPR repeat	123..148	CDD:276809	8/49 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1124
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900