Protein Alignment Spag1 and Ifit3b

DIOPT Version :9

• Sequence 1: NP_651514.1
• Gene: Spag1 / 43239
• FlyBaseID: FBgn0039463
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: XP_006527327.1
• Gene: Ifit3b / 667370
• MGIID: 3698419
• Length: 428
• Species: Mus musculus
• Alignment Length: 469
• Identity: 94/469 - (20%)
• Similarity: 165/469 - (35%)
• Gaps: 171/469 - (36%)

  Fly    47 GHYPDLQRCAEEKLKALKPDSK------LFRYEEQIKQSTDLDKTELKPILDWTDAIKTKDNALN 105
            ||.........|.|:|:.|..|      |||   :...|:.::                 |...|
Mouse    21 GHRRSQCEVNRESLEAILPQLKCHFTWNLFR---EGSMSSHME-----------------DRVCN 65

  Fly   106 ELKKVKQNLNLPSVRKLSKID-------LEKESKTEKPKPAPKATSPSNTKNKEARIKSTDYRKW 163
            :|:      :|.|..|.:..|       |:.|||..                .|...::.|.||
Mouse    66 QLE------HLNSEEKATMYDLLAYIKHLDGESKAA----------------LECLGQAEDLRK- 107

  Fly   164 DKYDPDEEILRMDLNEERDQEQREKIIS--NHSKSVTTDKLQSERDSLYERLQAQLKNLS----- 221
                          :|.:||.:..::::  |::.........||..:..::::...:..:
Mouse   108 --------------SEHKDQAEIRRLVTWGNYAWIYYHMGRLSEAQAYVDKVRQVCQKFANPYSM 158

  Fly   222 ---QLEKEQFAERHRLRGNESFKAKE-YENAIEEYNCSIIYDPENAVHAYNNRAVAHLKL----K 278
               :||.|:...|.:...||  :||. :|.|:||..    .|||    ..:..|:|..:|    :
Mouse   159 ECPELECEEGWTRLKCGRNE--RAKMCFEKALEEKP----KDPE----CSSGMAIAMFRLEEKPE 213

  Fly   279 KYFSAISDCQACLQIDPMN--IKA-----HLRMAEAHNAEGKHL---------ESLNVYKKLLDF 327
            |.|| :...:..::::|.|  :|.     .|||.|  .|||:.|         ...:|.:|...|
Mouse   214 KQFS-VDALKQAMELNPQNQYVKVLLALKLLRMGE--EAEGERLIKDALGKAPNQTDVLQKAAQF 275

  Fly   328 EPDNAIAKKAVEKLTSMLGEVAPSSAT--------RLIIEEIDPPQLKTSEPKKEAEKSE----- 379
            ........:|:|.|...|.....:|..        |.|:|::        :.|.:|:.||
Mouse   276 YKKKGNLDRAIELLGKALRSTVNNSPLYSLVMCRYREILEQL--------QNKGDADSSERRQRM 332

  Fly   380 ------------PTVVKKPEP------------------VVSAKKPPPIKDYDLAE----LVKPN 410
                        .|:.::..|                  :|.:|:.|.:::.||.|    |.:.:
Mouse   333 AELRRLTMEFMQKTLQRRRSPLNSYSDLIDFPEVERCYQMVISKESPDVEEEDLYERYCNLQEYH 397

  Fly   411 RMVKSNLVSAAEAL 424
            |  ||..::|.|.|
Mouse   398 R--KSEDLAALECL 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spag1	NP_651514.1	TPR_11	229..295	CDD:290150	18/70 (26%)
		TPR repeat	229..257	CDD:276809	9/28 (32%)
		TPR repeat	262..293	CDD:276809	6/34 (18%)
		TPR_11	266..329	CDD:290150	20/82 (24%)
		TPR	266..297	CDD:197478	7/34 (21%)
		TPR repeat	298..326	CDD:276809	11/41 (27%)
Ifit3b	XP_006527327.1	TPR repeat	76..104	CDD:276809	6/43 (14%)
		PEP_TPR_lipo	<81..>325	CDD:274350	59/295 (20%)
		TPR repeat	109..148	CDD:276809	6/38 (16%)
		TPR repeat	161..189	CDD:276809	10/29 (34%)
		TPR repeat	194..227	CDD:276809	9/37 (24%)
		TPR repeat	266..294	CDD:276809	6/27 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1124
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900