| Sequence 1: | NP_651514.1 | Gene: | Spag1 / 43239 | FlyBaseID: | FBgn0039463 | Length: | 469 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_149017.2 | Gene: | BBS4 / 585 | HGNCID: | 969 | Length: | 519 | Species: | Homo sapiens |
| Alignment Length: | 525 | Identity: | 99/525 - (18%) |
|---|---|---|---|
| Similarity: | 170/525 - (32%) | Gaps: | 171/525 - (32%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 2 EKEKKKS-----LLERYN--IPIHYLDFAHVEKCTNAREMEKIVQILRSGEEGHYPDLQRCAEEK 59
Fly 60 LKALKPDSKLFRYEEQIKQSTDLDKT--ELKPILDWTDAIKTKDNALNELKKVKQNLNLPSVRKL 122
Fly 123 SKIDLEKESKTEKPKPAPKATSPSNTKNKEARIKSTDYRKWDKYDPDEEILRMDLNEERDQEQRE 187
Fly 188 KIISNHSKSVTTDKLQSERDSLYERLQAQLKNLSQLEKE-----QFAERHRLRGNESFKAKEYEN 247
Fly 248 AIEEYNCSIIYDPENAVHAYNNRAVAHLKLKKYFSAISDCQACLQIDPMNIKAHLRMAEAHNAEG 312
Fly 313 KHLESLNVYKKLLDFEPD-----NAIA------KKAVEKLTSM----------------LGEV-- 348
Fly 349 ------------------APSSATRLIIEEIDPPQLKTSEPKKEAEKSEPTVVKKPEPVVS---- 391
Fly 392 ------AKKPPPIKDYDLAE----LVKPNRMVK--SNLVSAAEALGNKMQASKGGAPKKPQSPPM 444
Fly 445 TPKET 449 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Spag1 | NP_651514.1 | TPR_11 | 229..295 | CDD:290150 | 15/65 (23%) |
| TPR repeat | 229..257 | CDD:276809 | 7/27 (26%) | ||
| TPR repeat | 262..293 | CDD:276809 | 6/30 (20%) | ||
| TPR_11 | 266..329 | CDD:290150 | 14/62 (23%) | ||
| TPR | 266..297 | CDD:197478 | 7/30 (23%) | ||
| TPR repeat | 298..326 | CDD:276809 | 6/27 (22%) | ||
| BBS4 | NP_149017.2 | Required for localization to centrosomes | 1..66 | 10/60 (17%) | |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..25 | 1/5 (20%) | |||
| TPR_11 | <18..400 | CDD:330823 | 85/474 (18%) | ||
| TPR repeat | 36..61 | CDD:276809 | 5/38 (13%) | ||
| TPR 1 | 67..100 | 11/43 (26%) | |||
| TPR repeat | 68..95 | CDD:276809 | 8/26 (31%) | ||
| Interaction with PCM1. /evidence=ECO:0000269|PubMed:15107855 | 101..337 | 54/303 (18%) | |||
| TPR repeat | 101..129 | CDD:276809 | 9/53 (17%) | ||
| TPR repeat | 134..164 | CDD:276809 | 9/63 (14%) | ||
| TPR repeat | 169..196 | CDD:276809 | 7/33 (21%) | ||
| TPR repeat | 202..229 | CDD:276809 | 4/26 (15%) | ||
| TPR repeat | 236..264 | CDD:276809 | 6/27 (22%) | ||
| TPR repeat | 270..298 | CDD:276809 | 5/27 (19%) | ||
| TPR repeat | 303..333 | CDD:276809 | 3/29 (10%) | ||
| Required for localization to centrosomes | 338..519 | 24/113 (21%) | |||
| TPR repeat | 338..365 | CDD:276809 | 5/27 (19%) | ||
| TPR repeat | 372..397 | CDD:276809 | 4/24 (17%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 440..519 | 2/10 (20%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E2759_KOG1124 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.900 | |||||