DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Spag1 and Ifit1

DIOPT Version :9

Sequence 1:NP_651514.1 Gene:Spag1 / 43239 FlyBaseID:FBgn0039463 Length:469 Species:Drosophila melanogaster
Sequence 2:NP_064481.1 Gene:Ifit1 / 56824 RGDID:620599 Length:463 Species:Rattus norvegicus


Alignment Length:345 Identity:67/345 - (19%)
Similarity:121/345 - (35%) Gaps:110/345 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 EKKKSLLERYNIPIHY-LDFAHVEKCTNAREMEKIVQILRSGEEGHYPDLQRCAEEKLKALKPDS 67
            :|.:::...::.|..| ::.|.:: |      |:...:|:.| ..:|.....|.   .|||:.|.
  Rat   116 DKVENVCREFSSPFRYRMECAEID-C------EEGWALLKCG-GSNYMRAMACF---AKALQVDP 169

  Fly    68 KLFRYEE-----QIKQSTDLDKTELKPILDWTDAIKTKDNALNELKKVKQNLNLPSVR-----KL 122
            :...|..     ..:|..|.:...|:|:                .|.|:.|...|.::     ||
  Rat   170 ENPEYNAGYAVVAYRQDFDDNHVSLEPL----------------RKAVRLNPEDPHLKVLLALKL 218

  Fly   123 SKIDLEKESKTEKPKPAPKATSPSNTKNKEARIKSTDYRKWDKYDPDEEILRMDLNEERDQEQRE 187
            ..:..:.|::|.    ..:|.|.::.::...|..:..:|:           :.|:||......|.
  Rat   219 QDLGEQDEAETH----IEEALSSTSCQSYVFRYAAKYFRR-----------KGDINEALHLLHRA 268

  Fly   188 KIISNHSKSVTTDKLQSERDSLYERLQAQLKNLSQLEKEQFAERHRLRGNESFKAKEYENAIEEY 252
            .     ..|.::..|..::...|::...|||.               .||.  :|:..|| |:| 
  Rat   269 L-----QTSPSSGYLHYQKGLCYKQQMIQLKT---------------SGNR--QARRQEN-IQE- 309

  Fly   253 NCSIIYDPENAVHAYNNRAVAHLKLKKYFSAISDCQACLQIDPMNIKAHLRMAEA-------HNA 310
                               :||       .||.:.|..|.:.|....|::.|||.       ..|
  Rat   310 -------------------LAH-------QAICEFQETLNLRPTFEMAYVCMAEMQAEIGQYEEA 348

  Fly   311 EGKHLESLNVYKKLLDFEPD 330
            ||...|:||:...:...|.|
  Rat   349 EGNFQEALNLNNLVAHIEQD 368

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spag1NP_651514.1 TPR_11 229..295 CDD:290150 13/65 (20%)
TPR repeat 229..257 CDD:276809 7/27 (26%)
TPR repeat 262..293 CDD:276809 6/30 (20%)
TPR_11 266..329 CDD:290150 17/69 (25%)
TPR 266..297 CDD:197478 7/30 (23%)
TPR repeat 298..326 CDD:276809 10/34 (29%)
Ifit1NP_064481.1 TPR repeat 136..166 CDD:276809 9/40 (23%)
Coatomer_E 158..421 CDD:252768 58/295 (20%)
TPR repeat 171..203 CDD:276809 7/47 (15%)
TPR repeat 208..236 CDD:276809 6/31 (19%)
TPR repeat 242..270 CDD:276809 6/43 (14%)
TPR repeat 275..324 CDD:276809 18/93 (19%)
TPR repeat 329..356 CDD:276809 8/26 (31%)
TPR repeat 363..396 CDD:276809 2/6 (33%)
TPR repeat 426..454 CDD:276809
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.