DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spag1 and tmtc2a

DIOPT Version :9

Sequence 1:NP_651514.1 Gene:Spag1 / 43239 FlyBaseID:FBgn0039463 Length:469 Species:Drosophila melanogaster
Sequence 2:NP_001124075.1 Gene:tmtc2a / 564667 ZFINID:ZDB-GENE-041210-299 Length:844 Species:Danio rerio


Alignment Length:229 Identity:50/229 - (21%)
Similarity:81/229 - (35%) Gaps:76/229 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly   189 IISNHSKSVTTDKLQSERDSLYER--LQAQLKNLSQL--EKEQFAERHRLRGNESFKAKEYENAI 249
            ::.|..|....::  :.|::||.|  :...|.||..|  |.|:|:|                 |:
Zfish   510 VLKNQGKMAEAER--AYRNALYYRGNMADMLYNLGLLLQENERFSE-----------------AL 555

  Fly   250 EEYNCSIIYDPENAVHAYNNRAVAHLKLKKYFSAISDCQACLQIDPMNIK---AH--------LR 303
            ..|..:|...|..| .||.|..:..:.......|......|..|...|:|   ||        ..
Zfish   556 HYYKLAIGSRPTLA-SAYLNVGIILVSQGNIEEAKRTFHTCADIPDENLKDPHAHKSSVTSCLYN 619

  Fly   304 MAEAHNAEGKHLESLNVYKKL-------------------------------------LDFEPDN 331
            :.:..:.:|:|.|:|:|||:.                                     |..:||:
Zfish   620 LGKLLHDQGQHEEALSVYKEAVRKMPRQFAPQSLYNMMGEAYMRLNILEEAGHWYRESLKAKPDH 684

  Fly   332 AIAKKAVEKLTSMLGEVAPSSATRLIIE--EIDP 363
            ..|.....||.|::|:  .|.|.|..::  |:||
Zfish   685 IPAHLTYGKLLSIMGQ--KSEAERYFLKAIELDP 716

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spag1NP_651514.1 TPR_11 229..295 CDD:290150 12/65 (18%)
TPR repeat 229..257 CDD:276809 3/27 (11%)
TPR repeat 262..293 CDD:276809 6/30 (20%)
TPR_11 266..329 CDD:290150 18/110 (16%)
TPR 266..297 CDD:197478 6/30 (20%)
TPR repeat 298..326 CDD:276809 10/75 (13%)
tmtc2aNP_001124075.1 DUF1736 254..328 CDD:285594
TPR_11 501..562 CDD:290150 16/70 (23%)
TPR repeat 501..529 CDD:276809 3/20 (15%)
TPR_1 501..>528 CDD:278916 3/19 (16%)
TPR repeat 534..564 CDD:276809 11/46 (24%)
TPR_1 535..>562 CDD:278916 10/43 (23%)
TPR_12 565..642 CDD:290160 19/77 (25%)
TPR repeat 569..597 CDD:276809 6/28 (21%)
TPR repeat 603..642 CDD:276809 10/38 (26%)
TPR_2 617..646 CDD:285020 7/28 (25%)
TPR_11 653..716 CDD:290150 12/64 (19%)
TPR repeat 653..679 CDD:276809 0/25 (0%)
TPR repeat 684..714 CDD:276809 8/31 (26%)
TPR_8 685..716 CDD:289924 9/32 (28%)
TPR_16 757..820 CDD:290168
TPR_1 787..820 CDD:278916
TPR repeat 787..815 CDD:276809
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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