Protein Alignment Spag1 and ttc12

DIOPT Version :10

• Sequence 1: NP_651514.1
• Gene: Spag1 / 43239
• FlyBaseID: FBgn0039463
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: XP_009289931.1
• Gene: ttc12 / 563791
• ZFINID: ZDB-GENE-071016-4
• Length: 707
• Species: Danio rerio
• Alignment Length: 268
• Identity: 65/268 - (24%)
• Similarity: 113/268 - (42%)
• Gaps: 57/268 - (21%)

  Fly    85 TELKPILDWTDAIKTKDNALNELK-KVKQNLNLPSVRKLSKIDLEKESKTEKPKPAPKATSPSNT 148
            ::|:..|...|.|......||..: ..::|..:.:.:.:|.::.:::.||:..|   ...:.|::
Zfish    12 SDLEKFLRDVDQINELVRDLNSSEASCQENAIVKTEQLISSLEQKEQFKTKINK---TVINTSSS 73

  Fly   149 KNKEARIKSTDYRKWDKYDPDEEILRMDLNEERDQEQREKIISNHSKSVTTDKLQSERDSLYERL 213
            :|....|      :::.....|..|::...:..|:.||.|:
Zfish    74 ENNPLNI------RYESSQNPENFLKILEKDAEDRCQRRKM------------------------ 108

  Fly   214 QAQLKNLSQLEKEQFAERHRLRGNESFKAKEYENAIEEYNCSI--IYDPENAVHAYNNRAVAHLK 276
                       ||:.|...|.:|||:|...:||.|:..|...:  :.|.:   ..|.|||.|.:|
Zfish   109 -----------KEERANVLREQGNEAFTQGDYETAVRFYTEGLEQLRDMQ---ALYTNRAQAFIK 159

  Fly   277 LKKYFSAISDCQACLQIDPMNIKAHLRMAEAHNAEGKHLESLNVYKKLLDFEPDNAIAKKAV--- 338
            ||:|..|||||:..|:.:...|||.:.|..:|.|.....:|...|:|:|:.||......||.
Zfish   160 LKRYKEAISDCEWALRCNEKCIKAFIHMGTSHLALKDFTQSRICYRKILEIEPQRETMVKAYLRR 224

  Fly   339 ----EKLT 342
                ||:|
Zfish   225 VDMEEKVT 232

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spag1	NP_651514.1	NlpI	<229..373	CDD:443815	43/123 (35%)
		TPR repeat	229..257	CDD:276809	10/29 (34%)
		TPR repeat	262..293	CDD:276809	15/30 (50%)
		TPR repeat	298..326	CDD:276809	9/27 (33%)
ttc12	XP_009289931.1	TPR	107..>269	CDD:440225	46/164 (28%)
		TPR repeat	113..141	CDD:276809	10/27 (37%)
		TPR repeat	146..176	CDD:276809	15/32 (47%)
		TPR repeat	181..209	CDD:276809	9/27 (33%)
		CoV_Spike_S1-S2_S2	<298..>411	CDD:424070