DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spag1 and tmtc4

DIOPT Version :9

Sequence 1:NP_651514.1 Gene:Spag1 / 43239 FlyBaseID:FBgn0039463 Length:469 Species:Drosophila melanogaster
Sequence 2:NP_001166973.1 Gene:tmtc4 / 560605 ZFINID:ZDB-GENE-070912-148 Length:739 Species:Danio rerio


Alignment Length:211 Identity:44/211 - (20%)
Similarity:72/211 - (34%) Gaps:62/211 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   280 YFSAISDCQACLQIDPMNIKAHLRMAEAHNAEGKHLESLNVYKKLLDFEPDNAIAK--------- 335
            :.||:|.|       |:|.|.|..:.:.....|....::..|::.:...|....|.         
Zfish   469 FTSALSVC-------PLNAKVHYNVGKNLADRGNQSAAVQYYREAVRLHPKYVHAMNNLGNILKE 526

  Fly   336 ----KAVEKLTSMLGEVAPSSATRLIIEEIDPPQLKTSEPKKEAEKSEPTVVKKPEPVVSAKKPP 396
                |..|:|.|....:.|..|...:...|....||..   .:||:|....::       .:|..
Zfish   527 RNELKEAEELLSAAVHIQPDFAAAWMNLGIVQNSLKKF---NKAEQSYWNAIR-------FRKKY 581

  Fly   397 PIKDYDL-------------------AELVKPNR-MVKSNLVSAAEALGNKMQASKGGAPKKPQS 441
            |...|:|                   |.::||:. :..:|:|...:..||..||...|       
Zfish   582 PDCYYNLGRLYADLNRSIDALNAWRNATMLKPDHSLAWNNMVILLDNTGNLAQAELIG------- 639

  Fly   442 PPMTPKETLLRLPQDN 457
                 ||.|..||:|:
Zfish   640 -----KEALKILPKDH 650

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spag1NP_651514.1 TPR_11 229..295 CDD:290150 4/14 (29%)
TPR repeat 229..257 CDD:276809
TPR repeat 262..293 CDD:276809 4/12 (33%)
TPR_11 266..329 CDD:290150 10/48 (21%)
TPR 266..297 CDD:197478 5/16 (31%)
TPR repeat 298..326 CDD:276809 4/27 (15%)
tmtc4NP_001166973.1 DUF1736 291..363 CDD:312047
TPR 479..716 CDD:223533 39/194 (20%)
TPR repeat 480..508 CDD:276809 4/27 (15%)
TPR repeat 513..543 CDD:276809 5/29 (17%)
TPR repeat 548..576 CDD:276809 7/30 (23%)
TPR repeat 582..608 CDD:276809 3/25 (12%)
TPR repeat 618..644 CDD:276809 9/37 (24%)
TPR repeat 649..679 CDD:276809 1/2 (50%)
TPR repeat 684..712 CDD:276809
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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