DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spag1 and dnaaf4

DIOPT Version :9

Sequence 1:NP_651514.1 Gene:Spag1 / 43239 FlyBaseID:FBgn0039463 Length:469 Species:Drosophila melanogaster
Sequence 2:NP_001011174.1 Gene:dnaaf4 / 496594 XenbaseID:XB-GENE-959581 Length:411 Species:Xenopus tropicalis


Alignment Length:358 Identity:90/358 - (25%)
Similarity:143/358 - (39%) Gaps:72/358 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    20 LDFAHVEKCTNAREMEKIVQILRSGEEGHYPDLQRCAEEKLKA---LKPDSKLFRYEEQIKQSTD 81
            |..|::.|    .||:||       .|......|..|:::.||   .|.:::.:..|..:|    
 Frog    86 LTLANMGK----EEMQKI-------RENAVAKEQEKAQQETKARAERKRENEKYSLEVTMK---- 135

  Fly    82 LDKTELKPILDWTDAIKTKD--NALNELKKVK-----QNLNLPSVRKLSKIDLEKESKTEK---- 135
            ::..|.|.|.|    :|.::  .|..||:|.|     |.||    .|:.|..:.:|:::.|    
 Frog   136 IEDAERKRIED----VKHEERKKATEELEKWKEKERIQELN----EKIQKKQMRRENESNKAVHT 192

  Fly   136 --PKPAPKAT-----SPSNTKNKEARIKSTDYRKWDKYDPDEEILRMDLNEERDQEQREKIISNH 193
              .:....||     ||.|.|.||..:..|......:......:....|.|.|..|:.|.:   |
 Frog   193 RSSEHCSTATSVQNDSPVNVKQKEKILPPTRSTGCIQIQFTPRVFPTALRESRVAEEEEWL---H 254

  Fly   194 SKSVTTDKLQSERDSLYERLQAQLKNLSQLEKEQFAERHRLRGNESFKAKEYENAIEEYNCSIIY 258
            .        |:|.......:...|::|:..||.  .|..:.:||:.|.|.:...|:...|.:|..
 Frog   255 K--------QAEARRAINVVDPGLQDLTDEEKN--PEWLKDKGNKLFAAGDILAAVNALNLAIQL 309

  Fly   259 D---PENAVHAYNNRAVAHLKLKKYFSAISDCQACLQI--DPM------NIKAHLRMAEAHNAEG 312
            :   ||    .|.||:..||||:.....|.|....|::  .|:      .||||||...|.....
 Frog   310 NNKIPE----LYLNRSACHLKLRNLHKTIEDSSKALELLTPPVQGNASARIKAHLRRGTAFCELE 370

  Fly   313 KHLESLNVYKKLLDFEPDNAIAKKAVEKLTSML 345
            .::|.|..|:..|..:|.|...|...||:..::
 Frog   371 LYVEGLQDYETALKIDPTNQKVKSDAEKIRRII 403

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spag1NP_651514.1 TPR_11 229..295 CDD:290150 20/70 (29%)
TPR repeat 229..257 CDD:276809 7/27 (26%)
TPR repeat 262..293 CDD:276809 10/30 (33%)
TPR_11 266..329 CDD:290150 22/70 (31%)
TPR 266..297 CDD:197478 11/38 (29%)
TPR repeat 298..326 CDD:276809 10/27 (37%)
dnaaf4NP_001011174.1 co-chaperone p23-like domain 7..101 7/25 (28%)
p23_DYX1C1_like 10..86 CDD:107226 90/358 (25%)
PTZ00121 <93..>260 CDD:173412 47/200 (24%)
3a0801s09 273..>386 CDD:273380 35/118 (30%)
TPR repeat 280..308 CDD:276809 7/27 (26%)
TPR domain 283..388 31/108 (29%)
TPR repeat 313..343 CDD:276809 12/33 (36%)
TPR repeat 356..384 CDD:276809 10/27 (37%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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