DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Spag1 and dnaaf4

DIOPT Version :9

Sequence 1:NP_651514.1 Gene:Spag1 / 43239 FlyBaseID:FBgn0039463 Length:469 Species:Drosophila melanogaster
Sequence 2:NP_991251.1 Gene:dnaaf4 / 402988 ZFINID:ZDB-GENE-040426-1892 Length:420 Species:Danio rerio


Alignment Length:365 Identity:83/365 - (22%)
Similarity:140/365 - (38%) Gaps:75/365 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    28 CTNA-REMEK------IVQILRSGEEGHYPDLQRCAEEKLKALKPDSKLFRYE-EQIKQSTDLDK 84
            |||. :|.:|      ::::.....|.......|..:||..||:...||...| |:|::..|...
Zfish    87 CTNIDKEKQKQIREQAVLKVQEKAVEKSKTKATRIQQEKKYALETMMKLESEERERIQKRKDEVC 151

  Fly    85 TELKPILD-WTDA-IKTKDNALNELKKVKQNLNLPSVRKLSKIDLEKESKTEKPKPAPKATSPSN 147
            ......|| |.:. .||.....|::|                   |:.:.|...||.|:....:|
Zfish   152 ARATAELDFWRETQRKTAKGNENQIK-------------------EQRTSTHDNKPVPQKIKHAN 197

  Fly   148 TKNKEARIKSTD------YRKWDK----------------YDPDEEILRMDLNEERDQEQREKII 190
            |...:..:..||      .|...|                :.|  .:....|.|.|..|:.|.: 
Zfish   198 TSPADTALVKTDNTITGQMRSKQKTKDLPAPRSAGCIQISFTP--RVFPTALRESRVPEEEEWL- 259

  Fly   191 SNHSKSVTTDKLQSERDSLYERLQAQLKNLSQLEKEQFAERHRLRGNESFKAKEYENAIEEYNCS 255
                      |.|:|.....:...|:|.:|:  |.|:..:..:.:|::.|.|..:..|:..||.:
Zfish   260 ----------KKQAEARRAIDTDLAELDDLT--EDERNPDWLKDKGDKLFMAGNFLAAVNAYNLA 312

  Fly   256 IIYDPENAVHAYNNRAVAHLKLKKYFSAISDCQACLQI--------DPMNIKAHLRMAEAHNAEG 312
            |..:.:... .::|||..||||:....||.|....|::        ....:|||:|...|.....
Zfish   313 IKLNRKMPA-LFSNRAACHLKLRNLHKAIEDSSQALELLTPAVSANASARLKAHVRRGTAFCQLQ 376

  Fly   313 KHLESLNVYKKLLDFEPDNAIAKKAVEKLTSMLGEVAPSS 352
            .::|.|..|:|.|:.:|.||..:...|::..::....|.|
Zfish   377 LYVEGLQDYQKALEMDPHNAALRADTEQIRELIQGSTPRS 416

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spag1NP_651514.1 TPR_11 229..295 CDD:290150 18/73 (25%)
TPR repeat 229..257 CDD:276809 6/27 (22%)
TPR repeat 262..293 CDD:276809 11/30 (37%)
TPR_11 266..329 CDD:290150 21/70 (30%)
TPR 266..297 CDD:197478 11/38 (29%)
TPR repeat 298..326 CDD:276809 9/27 (33%)
dnaaf4NP_991251.1 p23_DYX1C1_like 10..87 CDD:107226 83/365 (23%)
TPR_11 285..349 CDD:290150 18/64 (28%)
TPR repeat 286..314 CDD:276809 6/27 (22%)
TPR_12 316..393 CDD:290160 21/77 (27%)
TPR repeat 319..349 CDD:276809 11/30 (37%)
TPR repeat 362..390 CDD:276809 9/27 (33%)
TPR_1 363..395 CDD:278916 11/31 (35%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
11.000

Return to query results.
Submit another query.