Protein Alignment Spag1 and BBS4

DIOPT Version :10

• Sequence 1: NP_651514.1
• Gene: Spag1 / 43239
• FlyBaseID: FBgn0039463
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_610636.1
• Gene: BBS4 / 36167
• FlyBaseID: FBgn0033578
• Length: 486
• Species: Drosophila melanogaster
• Alignment Length: 360
• Identity: 71/360 - (19%)
• Similarity: 132/360 - (36%)
• Gaps: 83/360 - (23%)

  Fly    18 HYLDFAHVEKCT--NAREMEKIVQILRS----GEEGHYPDLQRCAEEKLKALKPDSKLFRY--EE 74
            |.....|::|..  |.|.:|...:|.|:    |.......:.|.||:  ::.:.|.:::.|  |.
  Fly    83 HIEALRHLQKSAELNPRNIETYKEIGRTLYIMGRFSQALGVFREAEQ--RSSRQDHEIYHYLGEL 145

  Fly    75 QIKQSTDLDKTELKPILDWTDAIKTKDNALNELKKVKQNLNLPSVRKLSKIDLEKESKTEKPKPA 139
            ..:.:|...:.::        |.:.:|.|     :....|.:.|.|||
  Fly   146 LYRAATTQSQKDV--------ASQQQDEA-----RTYFELAVQSGRKL----------------- 180

  Fly   140 PKATSPSNTKNKEARIKSTD-YRKWDKYDPDEEILRMDLNEERDQEQREKIISNHSKSVTTDKLQ 203
                        |:.::..: |||..:|....|||...|:  ...|..|.:|......:..::.|
  Fly   181 ------------ESYVRLAELYRKDKQYQKAIEILENCLH--LTPENSEVLIEISVLYLKINETQ 231

  Fly   204 SERDSLYERLQAQLKNLSQLEKEQFAERHRLRGNESFKA-----KEYENAIEEYNCSIIYDPENA 263
            ...|.|.|.:..:.|...             :|..:|.|     .:.:.|:.:|:.....:||.|
  Fly   232 KAHDRLAEVVSIERKCSP-------------KGLLAFGAILQSRNDIDGALSKYSQIANAEPEIA 283

  Fly   264 VHAYNNRAVAHLKLKKYFSAISDCQACLQIDPMNIKAHLRMAEAHNAEGKHLESLNVYKKLLDFE 328
             ..:||..:...|.:|:..|||..:..:.:.|:|..|...::..:.|..::..:.:.....::..
  Fly   284 -ELWNNIGLCFFKKQKFIVAISSLRKSVWLSPLNYNALYNLSLIYIASEQYASAFHTLAAAINLR 347

  Fly   329 PDNA----IAKKAVEKLTSMLG-----EVAPSSAT 354
            .|||    :....:.||..|..     |.|.|.||
  Fly   348 KDNAECYMLLGLCLRKLDDMENAFVALERASSMAT 382

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spag1	NP_651514.1	NlpI	<229..373	CDD:443815	30/140 (21%)
		TPR repeat	229..257	CDD:276809	5/32 (16%)
		TPR repeat	262..293	CDD:276809	8/30 (27%)
		TPR repeat	298..326	CDD:276809	2/27 (7%)
BBS4	NP_610636.1	TPR repeat	68..95	CDD:276809	3/11 (27%)
		LapB	70..347	CDD:442196	60/323 (19%)
		TPR repeat	100..130	CDD:276809	7/31 (23%)
		TPR repeat	136..175	CDD:276809	7/51 (14%)
		TPR repeat	179..209	CDD:276809	11/60 (18%)
		TPR repeat	214..242	CDD:276809	6/27 (22%)
		TPR repeat	249..277	CDD:276809	5/40 (13%)
		BepA	281..423	CDD:443813	24/103 (23%)
		TPR repeat	283..311	CDD:276809	8/28 (29%)
		TPR repeat	316..346	CDD:276809	3/29 (10%)
		TPR repeat	351..377	CDD:276809	5/25 (20%)