DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spag1 and Sgt

DIOPT Version :10

Sequence 1:NP_651514.1 Gene:Spag1 / 43239 FlyBaseID:FBgn0039463 Length:469 Species:Drosophila melanogaster
Sequence 2:NP_609842.1 Gene:Sgt / 35052 FlyBaseID:FBgn0032640 Length:331 Species:Drosophila melanogaster


Alignment Length:345 Identity:76/345 - (22%)
Similarity:130/345 - (37%) Gaps:74/345 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   144 SPSNTKNKEARIKSTDYRKWDKYDPDEEILRMDLNEERDQEQREKIISNHSKSVTTDKLQSERDS 208
            ||..|::.|..|:... ..:|..| |.|.......||:...|.    |:.:.:...|.:.|....
  Fly    25 SPDQTESIEVAIQCLQ-AAFDLGD-DVEAAPAAAGEEQATTQS----SSTASAPDDDAVASGSAG 83

  Fly   209 LYERLQAQLKNLSQLEKEQ------------FAERHRLRGNESFKAKEYENAIEEYNCSIIYDPE 261
            :.....|...|:...|..|            .||..:..||...|..:|..|:.:||.:|.:||:
  Fly    84 IGAAAAAVPNNIDMFELFQSLYTERNPESLALAESIKNEGNRLMKENKYNEALLQYNRAIAFDPK 148

  Fly   262 NAVHAYNNRAVAHLKLKKYFSAISDCQACLQIDPMNIKAHLRMAEAHNAEGKHLESLNVYKKLLD 326
            |.:. |.|||.||::|.:...|::||::.|..:....||:.|:..|::..|...::...|.|.::
  Fly   149 NPIF-YCNRAAAHIRLGENERAVTDCKSALVYNNNYSKAYCRLGVAYSNMGNFEKAEQAYAKAIE 212

  Fly   327 FEPDNAIAKKAVEKLTSMLGEVAPSSATRLIIEEIDPPQLKTSEPKKEAEKSEPTVVKKPEPVVS 391
            .||||.:.|..:                               |..:.|....|...:..|.:::
  Fly   213 LEPDNEVYKSNL-------------------------------EAARNARNQPPQTGRLREDLIN 246

  Fly   392 AKKPPPIK------DYDLAELVK--PNRMVKSNLVSAAEALGNKMQASKGGAPKKPQSP-----P 443
            ....|.::      :.|:.:|:.  .|.|:.:.:         :.|...|.||..|...     .
  Fly   247 MLSQPMVRNLFNNAEIDVEQLLSMLQNPMIMNTI---------RQQFGGGNAPTLPNDMVQMIYN 302

  Fly   444 MTPKETLLRLPQDNLNNSNK 463
            ||.:  |...|..|.|..|:
  Fly   303 MTSQ--LTGFPNSNANPGNE 320

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spag1NP_651514.1 NlpI <229..373 CDD:443815 37/143 (26%)
TPR repeat 229..257 CDD:276809 9/27 (33%)
TPR repeat 262..293 CDD:276809 12/30 (40%)
TPR repeat 298..326 CDD:276809 7/27 (26%)
SgtNP_609842.1 SGTA_dimer 7..>48 CDD:465168 7/24 (29%)
TPR 116..>233 CDD:440225 38/148 (26%)
TPR repeat 116..144 CDD:276809 9/27 (33%)
TPR repeat 149..179 CDD:276809 12/30 (40%)
TPR repeat 184..212 CDD:276809 7/27 (26%)

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