DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spag1 and Tom70

DIOPT Version :10

Sequence 1:NP_651514.1 Gene:Spag1 / 43239 FlyBaseID:FBgn0039463 Length:469 Species:Drosophila melanogaster
Sequence 2:NP_609536.1 Gene:Tom70 / 34618 FlyBaseID:FBgn0032397 Length:589 Species:Drosophila melanogaster


Alignment Length:307 Identity:74/307 - (24%)
Similarity:115/307 - (37%) Gaps:99/307 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   126 DLEKESKTEKPKPAPKATSPSNTKNKEARIKSTDYRKWDKYDPDEEILRMDLNEERDQEQREKII 190
            :|:.|.|..|.|...:|.|...|.                  ||:|:       ||:|:..|   
  Fly    43 ELDGEKKRPKAKIEKQAISLDGTA------------------PDQEL-------ERNQKSAE--- 79

  Fly   191 SNHSKSVTTDKLQSERDSLYERLQAQLKNLSQLEKEQFAERHRLRGNESFKAKEYENAIEEYNCS 255
                              |.|:       ||.|::   |..::..||..::..:|:.||:.|:.:
  Fly    80 ------------------LGEK-------LSPLKE---ANNYKTEGNNCYRNGKYDEAIKFYDKA 116

  Fly   256 IIYDPENAVHA------YNNRAVAHLKLKKYFSAISDCQACLQIDPMNIKAHLRMAEAHNAE--- 311
            |...|:.  |.      |.|||.::..|||:.:...||.|.|:.:|...||:.|.|.||.|.   
  Fly   117 IDKCPKE--HRTDMAIFYQNRAASYEMLKKWSNVKEDCTASLEFNPRYAKAYYRRARAHEATKDM 179

  Fly   312 GKHLESLNVYKKLLDFEPDNAI-----AKKAVEKLTSMLG-----EVAPSSA-----TRLIIEEI 361
            .:.|:.:.....|..|:.:..|     ..|...:|.:..|     .|.||:.     ||..|  .
  Fly   180 NECLDDVTATCILEMFQNNQTIMFADRVLKETGRLDAEKGMRNRVPVVPSACFVNTYTRSFI--A 242

  Fly   362 DPPQ-LKTSEPKKEA--------------EKSEPTVVKKPEPVVSAK 393
            ||.| :|...||.:|              ||.|..:....|.:.|::
  Fly   243 DPLQTMKVPAPKSDAPPKGFLRAHLAFLEEKYEEIIPACTEEIESSE 289

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spag1NP_651514.1 NlpI <229..373 CDD:443815 47/168 (28%)
TPR repeat 229..257 CDD:276809 7/27 (26%)
TPR repeat 262..293 CDD:276809 12/36 (33%)
TPR repeat 298..326 CDD:276809 9/30 (30%)
Tom70NP_609536.1 3a0801s09 42..567 CDD:273380 74/307 (24%)
TPR repeat 90..118 CDD:276809 7/27 (26%)
TPR repeat 123..158 CDD:276809 12/36 (33%)
TPR repeat 296..324 CDD:276809
TPR repeat 334..362 CDD:276809
TPR repeat 367..397 CDD:276809
TPR repeat 402..437 CDD:276809
TPR repeat 443..471 CDD:276809
TPR repeat 476..507 CDD:276809
TPR repeat 512..539 CDD:276809
Blue background indicates that the domain is not in the aligned region.

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