DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Spag1 and CG4341

DIOPT Version :9

Sequence 1:	NP_651514.1	Gene:	Spag1 / 43239	FlyBaseID:	FBgn0039463	Length:	469	Species:	Drosophila melanogaster
Sequence 2:	NP_608558.1	Gene:	CG4341 / 33276	FlyBaseID:	FBgn0028481	Length:	938	Species:	Drosophila melanogaster

Alignment Length:	191	Identity:	39/191 - (20%)
Similarity:	71/191 - (37%)	Gaps:	51/191 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   180 ERDQEQREKIISNHSKSVTTDKLQSERDSLYERLQAQLKNLSQLEKEQFAERHRLRGNESFKAKE 244
            |:.:.||...|...:.| :...|..:|:.||:|:...|..|.|.::   ||||.
  Fly   727 EQGKLQRALAIYREALS-SLPGLPQQREILYQRIGDVLGRLQQWDE---AERHH----------- 776

  Fly   245 YENAIEEYNCSIIYDPENAVHAYNNRAVAHLK----LKKYFSAISDCQ----ACLQIDPMNIKAH 301
                            ..|:....|:..|||.    |.:..|..|:.:    ..|::.|.....:
  Fly   777 ----------------RAALELQPNQVAAHLSYGITLARNSSRASEAEMWFKRALKLAPEQASVY 825

  Fly   302 LRMAEAHNAEGKHLESLNVYKKLLDFEPDNAIAKKAVEKLTSMLGEVAPSSATRLIIEEID 362
            ...||..:.:.:|.||...:::..:..|::...            .||.::|.||:..::|
  Fly   826 HHYAEFLSLQSRHHESAIYHRRAAELAPNDYTL------------VVAAATAMRLLDRKVD 874

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spag1	NP_651514.1	TPR_11	229..295	CDD:290150	13/73 (18%)
		TPR repeat	229..257	CDD:276809	4/27 (15%)
		TPR repeat	262..293	CDD:276809	9/38 (24%)
		TPR_11	266..329	CDD:290150	14/70 (20%)
		TPR	266..297	CDD:197478	9/38 (24%)
		TPR repeat	298..326	CDD:276809	5/27 (19%)
CG4341	NP_608558.1	PMT_2	112..>232	CDD:304453
		DUF1736	275..343	CDD:285594
		TPR_11	602..667	CDD:290150
		TPR_1	602..634	CDD:278916
		TPR repeat	602..630	CDD:276809
		TPR repeat	635..665	CDD:276809
		TPR_11	636..700	CDD:290150
		TPR_1	636..668	CDD:278916
		TPR repeat	670..694	CDD:276809
		TPR_11	714..784	CDD:290150	18/87 (21%)
		TPR repeat	715..743	CDD:276809	4/15 (27%)
		TPR repeat	748..782	CDD:276809	13/63 (21%)
		TPR_11	755..819	CDD:290150	19/93 (20%)
		TPR repeat	787..816	CDD:276809	6/28 (21%)
		TPR_11	821..887	CDD:290150	12/66 (18%)
		TPR repeat	822..850	CDD:276809	5/27 (19%)
		TPR repeat	855..885	CDD:276809	6/32 (19%)
		TPR_11	<874..921	CDD:290150	1/1 (100%)
		TPR repeat	890..918	CDD:276809
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1124
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900