Protein Alignment Spag1 and stub1

DIOPT Version :10

• Sequence 1: NP_651514.1
• Gene: Spag1 / 43239
• FlyBaseID: FBgn0039463
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_955968.2
• Gene: stub1 / 324243
• ZFINID: ZDB-GENE-030131-2963
• Length: 287
• Species: Danio rerio
• Alignment Length: 281
• Identity: 66/281 - (23%)
• Similarity: 124/281 - (44%)
• Gaps: 43/281 - (15%)

  Fly   218 KNLSQLEKEQFAERHRLRGNESFKAKEYENAIEEYNCSIIYDPENAVHAYNNRAVAHLKLKKYFS 282
            |..|..||...|:..:.:||..|.:::|:.|:..|:.:|..:|..||: |.|||:.::||::|..
Zfish     3 KMASSPEKSSSAQELKEQGNRLFLSRKYQEAVTCYSKAINRNPSVAVY-YTNRALCYVKLQQYDK 66

  Fly   283 AISDCQACLQIDPMNIKAH-------LRMAEAHNAEGKHLESLNVYK-KLLDFEPD----NAIAK 335
            |::||:..|::|..::|||       |.:.....|.|....:.|:.| :.|:|..|    ..|||
Zfish    67 ALADCKHALELDSQSVKAHFFLGQCQLELENYEEAIGNLQRAYNLAKEQRLNFGDDIPSALRIAK 131

  Fly   336 K-----AVEKLTSMLGEVAPSSATRLIIE---EIDPPQLKTSEP-------KKEAEKSEPTVVKK 385
            |     ..||..|...|:....:..::.|   |:| .::|.|:.       .|...|.:..::..
Zfish   132 KKRWNSIEEKRISQENELHAYLSKLILAEKERELD-DRVKQSDDSQNGGDISKMKSKHDKYLMDM 195

  Fly   386 PE---PVVSAKKPPPIKDYDLAEL---------VKPNRMV--KSNLVSAAEALGNKMQASKGGAP 436
            .|   .|...:|...|.||...::         :.|:.:.  :.::....:.:|:....::....
Zfish   196 DELFSQVDEKRKKREIPDYLCGKISFELMREPCITPSGITYDRKDIEEHLQRVGHFDPVTRSPLT 260

  Fly   437 KKPQSPPMTPKETLLRLPQDN 457
            :....|.:..||.:....|:|
Zfish   261 QDQLIPNLAMKEVIDAFIQEN 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spag1	NP_651514.1	NlpI	<229..373	CDD:443815	47/170 (28%)
		TPR repeat	229..257	CDD:276809	7/27 (26%)
		TPR repeat	262..293	CDD:276809	13/30 (43%)
		TPR repeat	298..326	CDD:276809	8/35 (23%)
stub1	NP_955968.2	NlpI	<14..133	CDD:443815	37/119 (31%)
		TPR repeat	14..42	CDD:276809	7/27 (26%)
		TPR repeat	47..77	CDD:276809	13/30 (43%)
		TPR repeat	82..109	CDD:276809	6/26 (23%)
		CHIP_TPR_N	130..209	CDD:436460	17/79 (22%)
		RING-Ubox_CHIP	211..281	CDD:438316	9/69 (13%)