Protein Alignment Spag1 and Tomm34

DIOPT Version :10

• Sequence 1: NP_651514.1
• Gene: Spag1 / 43239
• FlyBaseID: FBgn0039463
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_001037709.1
• Gene: Tomm34 / 311621
• RGDID: 1309029
• Length: 309
• Species: Rattus norvegicus
• Alignment Length: 337
• Identity: 77/337 - (22%)
• Similarity: 133/337 - (39%)
• Gaps: 79/337 - (23%)

  Fly    35 EKIVQILRSGEE----GHYPDLQRCAEEKLKALK------PDSKLFRYEEQ-------------I 76
            :.:.|:..:|.:    |.|.:.....|..|:.|:      |:.:...|..:             |
  Rat     7 DSVEQLRAAGNQNFRNGQYGEASALYERALRLLQARGSADPEEESVLYSNRAACYLKDGNCTDCI 71

  Fly    77 KQSTD---LDKTELKPILDWTDAIKTKDN---ALNELKKVKQNLN-----LPSVRKLSKIDLEKE 130
            |..|.   |....:||:|....|.:..:.   |..:.|.|.|..|     |..:.::::..::..
  Rat    72 KDCTSALALVPFSIKPLLRRASAYEALEKYSLAYVDYKTVLQIDNSVASALEGINRITRALMDSL 136

  Fly   131 SKTEKPKPAPKATSPSNTKNKEARIKSTDYRKWDKYDPDEEILRMDLNEERDQEQREKIISNHSK 195
            ....:.|..|....|.:.:.:.:.:.|.::::..|                          :.||
  Rat   137 GPEWRLKLPPIPVVPVSAQKRWSSLPSENHKETAK--------------------------SKSK 175

  Fly   196 SVTTDKLQSERDSLYERLQAQLKNLSQLEKEQFAERHRLRGNESFKAKEYENAIEEYNCSIIYDP 260
            ..|..|.:.......||        :::.||:        |||..|...::.|||:|:.|:::..
  Rat   176 ETTATKNRVPSAGDVER--------ARVLKEE--------GNELVKKGNHKKAIEKYSESLLFSS 224

  Fly   261 -ENAVHAYNNRAVAHLKLKKYFSAISDCQACLQIDPMNIKAHLRMAEAHNAEGKHLESLNVYKKL 324
             |:|  .|:|||:.||.||:|..|..||...|::|..|:||..|.|:|:.|...:..||.....|
  Rat   225 LESA--TYSNRALCHLVLKQYKEAEKDCTEALKLDGKNVKAFYRRAQAYKALKDYKSSLADISSL 287

  Fly   325 LDFEPDNAIAKK 336
            |..||.|..|.|
  Rat   288 LQIEPRNGPAHK 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spag1	NP_651514.1	NlpI	<229..373	CDD:443815	41/109 (38%)
		TPR repeat	229..257	CDD:276809	9/27 (33%)
		TPR repeat	262..293	CDD:276809	14/30 (47%)
		TPR repeat	298..326	CDD:276809	9/27 (33%)
Tomm34	NP_001037709.1	TPR 1	9..42		7/32 (22%)
		TPR repeat	9..37	CDD:276809	5/27 (19%)
		3a0801s09	<11..>294	CDD:273380	74/326 (23%)
		TPR repeat	50..80	CDD:276809	4/29 (14%)
		TPR 2	51..84		5/32 (16%)
		TPR repeat	85..113	CDD:276809	7/27 (26%)
		TPR 3	86..118		9/31 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	158..187		6/54 (11%)
		TPR 4	193..226		11/40 (28%)
		TPR repeat	193..221	CDD:276809	11/35 (31%)
		TPR repeat	226..256	CDD:276809	15/31 (48%)
		TPR 5	227..260		15/34 (44%)
		TPR repeat	261..289	CDD:276809	9/27 (33%)
		TPR 6	262..294		12/31 (39%)