Protein Alignment Spag1 and Ifit3

DIOPT Version :10

• Sequence 1: NP_651514.1
• Gene: Spag1 / 43239
• FlyBaseID: FBgn0039463
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_001007695.1
• Gene: Ifit3 / 309526
• RGDID: 1359681
• Length: 411
• Species: Rattus norvegicus
• Alignment Length: 429
• Identity: 86/429 - (20%)
• Similarity: 162/429 - (37%)
• Gaps: 101/429 - (23%)

  Fly    30 NAREMEKIV---------QILRSGEEGHYPDLQRCAEEKLKALKPDSKLFRYE------------ 73
            |...:|||:         .:.:.|....:.:.:.|  .:::.|..:.|...|:
  Rat     5 NKESLEKILPQLKCHFTWNLFKEGSISSHMEDRVC--NQIENLNSEHKATMYDLLAYIKHLDGEN 67

  Fly    74 ----------EQIKQSTDLDKTELKPILDWTDA--IKTKDNALNE-------LKKVKQNLNLPSV 119
                      |.:::|...|:.|:|.::.|.:.  |..:...|:|       :::|.|....|..
  Rat    68 EAALECLGQAEDLRKSERSDRAEIKCLVTWGNYAWIYYRIGQLSEAQAYADKVRQVCQKFANPYS 132

  Fly   120 RKLSKIDLE------KESKTEKPKPAPKATSPSNTKNKEAR--IKSTDYRKWDKYDPDEEI---- 172
            .:..::|.|      |..:.|:.|...:.......::.|.|  :....||..:|  |:::.
  Rat   133 MECPELDCEEGWTRLKCGRNERAKMCFEKALEEKPEDPECRAGMAIAMYRLQEK--PEKQFSVDA 195

  Fly   173 --LRMDLNEERDQEQREKIISNHSKSVTTDKLQSERDSLYERL--QAQLKNLSQLE-KEQFAERH 232
              ..|:||   .|.|.||::    .::...|:..|.::  |||  .|..|..:|.: .::.|:.:
  Rat   196 LKQAMELN---SQNQYEKVL----LALKLQKMGEEAEA--ERLVEDALEKGPNQTDVLQKAAQFY 251

  Fly   233 RLRGNESFKAKEYENAIEEYNCSIIYDPENAVHAYNNRAVAHLKLKKYFSAISDCQACLQID--- 294
            |.:||       .:.|||....::       ....||..:..|.:.:|...:...|...:.|
  Rat   252 RKKGN-------LDRAIEFLGKAL-------RSTANNSPLYSLVMCRYREKLKQLQNTGEADKSE 302

  Fly   295 ---PMNIKAHLRMAEAHNAEGKHLESLNVYKKLLDFEPDNAIAKKAVEKLTSML-GEVAPSSATR 355
               .|.....|.|...:.|..:....||.|..|:|| |:       |||...|: .|.:|.:..:
  Rat   303 RRQTMEELRRLTMEYMNKALQRRPSPLNSYSDLIDF-PE-------VEKCYQMVFSEESPRAEDQ 359

  Fly   356 LIIEEIDPPQLKTSEPKKEAEKSEPTVVKKPEPVVSAKK 394
            .:.|..  ..|:....|.|..|:...:::.|.|..|.:|
  Rat   360 ELFERY--CNLQEYHRKSEGLKALKDLMQFPRPEKSTEK 396

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spag1	NP_651514.1	NlpI	<229..373	CDD:443815	32/150 (21%)
		TPR repeat	229..257	CDD:276809	7/27 (26%)
		TPR repeat	262..293	CDD:276809	5/30 (17%)
		TPR repeat	298..326	CDD:276809	7/27 (26%)
Ifit3	NP_001007695.1	TPR_12	51..126	CDD:315987	11/74 (15%)
		TPR repeat	51..79	CDD:276809	1/27 (4%)
		TPR repeat	93..123	CDD:276809	4/29 (14%)
		TPR	96..325	CDD:440225	50/253 (20%)
		TPR repeat	136..164	CDD:276809	5/27 (19%)
		TPR repeat	206..236	CDD:276809	9/35 (26%)
		TPR repeat	241..269	CDD:276809	7/41 (17%)