Protein Alignment Spag1 and Bbs4

DIOPT Version :9

• Sequence 1: NP_651514.1
• Gene: Spag1 / 43239
• FlyBaseID: FBgn0039463
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: XP_038937022.1
• Gene: Bbs4 / 300754
• RGDID: 1309134
• Length: 529
• Species: Rattus norvegicus
• Alignment Length: 479
• Identity: 94/479 - (19%)
• Similarity: 159/479 - (33%)
• Gaps: 156/479 - (32%)

  Fly    51 DLQRC---AEEKLK--------ALKPDSKLFRYEEQIKQSTDLDKT--ELKPILDWTDAIKTKDN 102
            |.:.|   .:|:|:        |:...:.:||.|..|::|.:|.:|  .|.|        :..||
  Rat    56 DYEACKAVIKEQLQETQGLCEYAIYVQALIFRLEGNIQESLELFQTCAVLSP--------QCADN 112

  Fly   103 ALNELKKVKQNLNLPSVRKLSKIDLEKESKTEKPKPAPKATSPSNTKNKEARIKSTDYRKWDKYD 167
                ||:|.::|.|....|                      :.:...|:.|::...|:
  Rat   113 ----LKQVARSLFLLGKHK----------------------AATEVYNEAAKLNQKDW------- 144

  Fly   168 PDEEILRMDLNEERDQEQREKIISNHSKSVTTDKLQSERDSLYERLQAQLKNLSQLEKE-----Q 227
               ||.                   |:..|....|:.     :.:.|.||.:..||.|.     .
  Rat   145 ---EIC-------------------HNLGVCYTYLKQ-----FSKAQDQLHSALQLNKHDLTYIM 182

  Fly   228 FAERHRLRGNESFKAKEYENAIEEYNCSIIYDPENAVHAYNNRAVAHLKLKKYFSAISDCQACLQ 292
            ..:.|.|:|       :.:.|||.|..::.:.||| ........:.:|:|..|..|.......|.
  Rat   183 LGKIHLLQG-------DLDKAIEIYKKAVEFSPEN-TELLTTLGLLYLQLGVYQKAFEHLGNALT 239

  Fly   293 IDPMNIKAHLRMAEAHNAEGKHLESLNVYKKLLDFEPD-----NAIA------KKAVEKLTSM-- 344
            .||.|.||.|.........|....:|..|:.:....|:     |.|.      ||.|..::.:
  Rat   240 YDPANYKAILAAGSMMQTHGDFDVALTKYRVVACAIPESPPLWNNIGMCFFGKKKYVAAISCLKR 304

  Fly   345 LGEVAP-------------------SSATRLIIEEID-PPQ-----------LKTSEPKKEAEKS 378
            ...:||                   :||...:...|: .|:           |...|..:.|:::
  Rat   305 ANYLAPFDWKILYNLGLVHLTMQQYASAFHFLSAAINFQPKMGELYMLLAVALTNLEDIENAKRA 369

  Fly   379 --EPTVVKKPEPVVS----------AKKPPPIKDYDLAE----LVKPNRMVK--SNLVSAAEALG 425
              |...:.|..|:|:          .:|...:..|...|    .:|.|..::  |.:|..|:.||
  Rat   370 YVEAVRLDKCNPLVNLNYAVLLYNQGEKKGALAQYQEMEKKVHFLKDNNPLEFDSEMVEMAQKLG 434

  Fly   426 NKMQASKGGAPKKPQSPPMTPKET 449
            ..:|..:.....||...|.:...|
  Rat   435 AALQVGEALVWTKPVKDPKSKHRT 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spag1	NP_651514.1	TPR_11	229..295	CDD:290150	15/65 (23%)
		TPR repeat	229..257	CDD:276809	7/27 (26%)
		TPR repeat	262..293	CDD:276809	6/30 (20%)
		TPR_11	266..329	CDD:290150	14/62 (23%)
		TPR	266..297	CDD:197478	7/30 (23%)
		TPR repeat	298..326	CDD:276809	6/27 (22%)
Bbs4	XP_038937022.1	PEP_TPR_lipo	<31..442	CDD:274350	90/461 (20%)
		TPR repeat	77..104	CDD:276809	8/26 (31%)
		TPR repeat	110..138	CDD:276809	9/53 (17%)
		TPR repeat	143..173	CDD:276809	9/63 (14%)
		TPR repeat	178..205	CDD:276809	7/33 (21%)
		TPR repeat	211..238	CDD:276809	4/26 (15%)
		TPR repeat	245..273	CDD:276809	6/27 (22%)
		TPR repeat	279..307	CDD:276809	5/27 (19%)
		TPR repeat	312..342	CDD:276809	3/29 (10%)
		TPR repeat	347..375	CDD:276809	4/27 (15%)
		TPR repeat	381..406	CDD:276809	4/24 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1124
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900