DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spag1 and Ifit1bl

DIOPT Version :9

Sequence 1:NP_651514.1 Gene:Spag1 / 43239 FlyBaseID:FBgn0039463 Length:469 Species:Drosophila melanogaster
Sequence 2:XP_220058.2 Gene:Ifit1bl / 294090 RGDID:1304872 Length:473 Species:Rattus norvegicus


Alignment Length:458 Identity:97/458 - (21%)
Similarity:158/458 - (34%) Gaps:151/458 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly    13 YNIPIHYLDFAHVEKCTNAREMEKIVQILRSGE---EG-----------------HY-----PDL 52
            ||:.:|.| .|:|.....  |.|:.:|.|:..|   ||                 ||     .:.
  Rat    58 YNMGMHNL-MAYVRHLKG--EQEEALQSLKEAEALIEGEQLGKRSLVTWGNCAWVHYHRGSLAEA 119

  Fly    53 QRCAEEKLKALKPDSKLFRYEEQIKQSTDLDKTELKPIL-----DWTDAIKTKDNAL-------- 104
            |...::.....:..:..|||.   .:..::|..|...:|     :.|.|:.....||        
  Rat   120 QIYLDKVENVCREFASPFRYR---MECAEIDCEEGWALLKCGGSNCTRAMACFAKALQEEPENPE 181

  Fly   105 ---------------NEL------KKVKQNLNLPSVRKLSKI---DLEKESKTEK--PKPAPKAT 143
                           ||:      |.|:.|...|.::.|..:   ||.|:.:.||  .:..||..
  Rat   182 YNAGYAITAFRMDFSNEISLEPLRKAVRLNPEDPHLKVLLALKLQDLGKQDEAEKHIEEALPKIP 246

  Fly   144 SPSNTKNKEARIKSTDYRKWDKYDPDEEILRMDLNEERDQEQREKIISNHSKSVTTDKLQSERDS 208
            |.:|.....|:.    ||:....:...|.|      ||                   .|:::..|
  Rat   247 SRNNIFGYVAKF----YRRKGCVEEALEFL------ER-------------------ALKTKPSS 282

  Fly   209 LYERLQAQLKNLSQLEKEQFAERHRLRGNESFKAKEYENAIEEYNCSIIYDPENA------VHAY 267
            :|...|..|.:.|::.:.:.|.      |...|.|:.|.|.:....:|.|..:..      ..||
  Rat   283 VYLHFQIGLCHKSRVFQIKEAT------NMHPKGKDRERADQSIRSAIYYFEKTLDLKPTYERAY 341

  Fly   268 NNRAVAHLKLKKYFSAISDCQACLQIDPMNIKAHLRMAEAHNAEGK----HLESLNV----YKKL 324
            .:.|..:.:.|::..|....|..|.: ..|::.|::. |.|...||    |::|.|:    |.|.
  Rat   342 IDLAEMYAESKQFEEAEEAFQKVLSM-LSNLEVHMQQ-EIHFRYGKFQQFHMKSENIAITHYLKG 404

  Fly   325 LDFEPDNAIAK---KAVEKLT--------------SMLGEV------------APSSATRLIIEE 360
            |..|..:....   ||::||.              |:||.|            ....|.|| .||
  Rat   405 LKIEVTSIFRDKLLKALQKLAERRMQQNVHVLESLSLLGFVYRLKGDTRKAMSCYEKALRL-TEE 468

  Fly   361 IDP 363
            ::|
  Rat   469 LNP 471

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spag1NP_651514.1 TPR_11 229..295 CDD:290150 15/71 (21%)
TPR repeat 229..257 CDD:276809 6/27 (22%)
TPR repeat 262..293 CDD:276809 7/36 (19%)
TPR_11 266..329 CDD:290150 19/70 (27%)
TPR 266..297 CDD:197478 7/30 (23%)
TPR repeat 298..326 CDD:276809 10/35 (29%)
Ifit1blXP_220058.2 TPR_12 62..132 CDD:290160 14/72 (19%)
TNFRSF <124..>167 CDD:304602 8/45 (18%)
TPR repeat 144..174 CDD:276809 6/29 (21%)
TPR_11 214..280 CDD:290150 19/94 (20%)
TPR repeat 214..244 CDD:276809 7/29 (24%)
TPR repeat 282..333 CDD:276809 13/56 (23%)
TPR repeat 338..366 CDD:276809 6/27 (22%)
TPR repeat 371..406 CDD:276809 10/35 (29%)
TPR repeat 412..464 CDD:276809 9/51 (18%)
TPR_1 437..473 CDD:278916 10/36 (28%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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