DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spag1 and Ogt

DIOPT Version :9

Sequence 1:	NP_651514.1	Gene:	Spag1 / 43239	FlyBaseID:	FBgn0039463	Length:	469	Species:	Drosophila melanogaster
Sequence 2:	XP_006257118.1	Gene:	Ogt / 26295	RGDID:	62060	Length:	1046	Species:	Rattus norvegicus

Alignment Length:	167	Identity:	36/167 - (21%)
Similarity:	63/167 - (37%)	Gaps:	37/167 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   217 LKNLSQLEKEQ-------------------FAERHRLRGNESFKAKEYENAIEEYNCSIIYDPEN 262
            |.||:.:::||                   ||..|....:...:..:.:.|:..|..:|...|..
  Rat   330 LNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTF 394

  Fly   263 AVHAYNNRAVAHLKLKKYFSAISDCQACLQIDPMNIKAHLRMAEAHNAEGKHLESLNVYKKLLDF 327
            | .||:|......:::....|:......:||:|....||..:|..|...|...|::..|:..|..
  Rat   395 A-DAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKL 458

  Fly   328 EPD--NAIAKKA---------------VEKLTSMLGE 347
            :||  :|....|               ::||.|::.|
  Rat   459 KPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVAE 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spag1	NP_651514.1	TPR_11	229..295	CDD:290150	13/65 (20%)
		TPR repeat	229..257	CDD:276809	4/27 (15%)
		TPR repeat	262..293	CDD:276809	5/30 (17%)
		TPR_11	266..329	CDD:290150	15/62 (24%)
		TPR	266..297	CDD:197478	7/30 (23%)
		TPR repeat	298..326	CDD:276809	7/27 (26%)
Ogt	XP_006257118.1	PEP_TPR_lipo	<22..>465	CDD:274350	30/135 (22%)
		TPR repeat	24..49	CDD:276809
		TPR repeat	57..83	CDD:276809
		TPR repeat	89..117	CDD:276809
		TPR repeat	122..152	CDD:276809
		TPR repeat	157..185	CDD:276809
		TPR repeat	191..219	CDD:276809
		TPR repeat	226..253	CDD:276809
		TPR repeat	259..287	CDD:276809
		TPR repeat	293..321	CDD:276809
		TPR repeat	327..355	CDD:276809	5/24 (21%)
		TPR repeat	360..390	CDD:276809	6/29 (21%)
		TPR repeat	395..423	CDD:276809	5/28 (18%)
		TPR repeat	429..457	CDD:276809	7/27 (26%)
		Glyco_transf_41	476..1016	CDD:404688	4/20 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1124
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900