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Protein Alignment Spag1 and Kdm6a

DIOPT Version :10

Sequence 1:	NP_651514.1	Gene:	Spag1 / 43239	FlyBaseID:	FBgn0039463	Length:	469	Species:	Drosophila melanogaster
Sequence 2:	XP_006527657.1	Gene:	Kdm6a / 22289	MGIID:	1095419	Length:	1476	Species:	Mus musculus

Alignment Length:	440	Identity:	89/440 - (20%)
Similarity:	157/440 - (35%)	Gaps:	122/440 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   101 DNALNELKKVKQNLNLPSVRKLSKIDLEKESKTEKPKPAPKATSPSNTKNKEARIKSTD-YRKWD 164
            |.:....|::...|.|     :.|::.:.||..:..:.|....:|....|.|.:..... |....
Mouse   162 DPSFCRAKEIHLRLGL-----MFKVNTDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQR 221

  Fly   165 KYDPDEEILRMDLNEERDQEQREKII------SNHSKSVTTDKLQSERDSLYERLQAQL------ 217
            ||...:|.....|..|....|.:..|      .:|:..:..||...|..:: :.||..|
Mouse   222 KYHSAKEAYEQLLQTENLSAQVKATILQQLGWMHHTVDLLGDKATKESYAI-QYLQKSLEADPNS 285

  Fly   218 --------KNLSQLEKEQFAERHRLRGNESFKAKEYENAIEEYN------CSI--IYDPEN---- 262
                    :..|.:.|.|          ::|.:  |..:|::..      |||  :|..:|
Mouse   286 GQSWYFLGRCYSSIGKVQ----------DAFIS--YRQSIDKSEASADTWCSIGVLYQQQNQPMD 338

  Fly   263 AVHAY-------NNRAVAHLKLKKYFSAISDCQACLQIDPMN-IKAHLRMAEAHNAEGKHLESLN 319
            |:.||       :..|.|.:.|...:      ::|.|  |.: ||.:|....:.|.  .:...|.
Mouse   339 ALQAYICAVQLDHGHAAAWMDLGTLY------ESCNQ--PQDAIKCYLNATRSKNC--SNTSGLA 393

  Fly   320 VYKKLLDFEPDNAIAKKAVEKLTSMLGEVAPSSATRLIIEEI----DPPQLKTSEP--------- 371
            ...|.|..:..| :.:.:::..|.:|    ||      |||.    .|.:|.:.:.
Mouse   394 ARIKYLQAQLCN-LPQGSLQNKTKLL----PS------IEEAWSLPIPAELTSRQGAMNTAQQAC 447

  Fly   372 KKEAEKSEPTVVKKPEPVVSAKKP----PPIKDYDLAELVKPNRMVKSNLVSAAEALGNKMQASK 432
            |.....:||.:.....|:.....|    ||.:..||:...|..|       :::.........|.
Mouse   448 KPHHPNTEPVLGLSQTPISQQSLPLHMIPPSQVDDLSSPAKRKR-------TSSPTKNTSDNWSG 505

  Fly   433 GGAPKKPQSPP---------MTPKE----TLLRLPQDNLNNSNKLLIQEI 469
            |.||     ||         :||::    ..||..::|||.:.||:::::
Mouse   506 GNAP-----PPVEQQTHSWCLTPQKLQHLEQLRANRNNLNPAQKLMLEQL 550

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.